Amiloride: Difference between revisions
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Amiloride is a drug used to treat [[Hypertension|hypertension]] ( high [[Blood pressure|blood pressure]] ). It is a "potassium-sparing" [[Diuretic|diuretic that]] acts by blocking [[ | Amiloride is a drug used to treat [[Hypertension|hypertension]] ( high [[Blood pressure|blood pressure]] ). It is a "potassium-sparing" [[Diuretic|diuretic that]] acts by blocking [[Enac|Enac]] (epithelial sodium channel) inhibiting the reabsorption of [[Sodium|sodium]] by the distal convoluted tubules and collecting ducts within the [[Kidneys|kidneys]]. By doing this it promotes the excretion of [[Sodium|sodium]] and [[Water|water]] from the bloodstream, thereby reducing blood pressure. | ||
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[http://www.google.co.uk/imgres?imgurl=http://www.medicinescomplete.com/mc/martindale/2009/images/CLK0081C001.gif&imgrefurl=http://www.medicinescomplete.com/mc/martindale/2009/2304-d.htm&usg=__L8bOh4b1SkQBIAGIu07PBPtG1HA=&h=76&w=163&sz=4&hl=en&start=8&zoom=0&itbs=1&tbnid=_h97Mte0OTxqpM:&tbnh=46&tbnw=98&prev=/images%3Fq%3Damiloride%2Bstructure%26hl%3Den%26gbv%3D2%26tbs%3Disch:1 [[Image:Amiloride structure.gif|This details the chemical structure of amiloride]]] | [http://www.google.co.uk/imgres?imgurl=http://www.medicinescomplete.com/mc/martindale/2009/images/CLK0081C001.gif&imgrefurl=http://www.medicinescomplete.com/mc/martindale/2009/2304-d.htm&usg=__L8bOh4b1SkQBIAGIu07PBPtG1HA=&h=76&w=163&sz=4&hl=en&start=8&zoom=0&itbs=1&tbnid=_h97Mte0OTxqpM:&tbnh=46&tbnw=98&prev=/images%3Fq%3Damiloride%2Bstructure%26hl%3Den%26gbv%3D2%26tbs%3Disch:1 [[Image:Amiloride structure.gif|This details the chemical structure of amiloride]]] | ||
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Revision as of 15:51, 15 November 2010
Amiloride is a drug used to treat hypertension ( high blood pressure ). It is a "potassium-sparing" diuretic that acts by blocking Enac (epithelial sodium channel) inhibiting the reabsorption of sodium by the distal convoluted tubules and collecting ducts within the kidneys. By doing this it promotes the excretion of sodium and water from the bloodstream, thereby reducing blood pressure.
Its chemical structure is detailed below:
References
http://www.pharmgkb.org/views/index.jsp?objId=PA448368#tabview=tab1
http://www.medicinescomplete.com/mc/martindale/2009/images/CLK0081C001.gif
