Carrier: Difference between revisions
Jump to navigation
Jump to search
Created page with "A carrier is an organism that carries a disease without showing any signs or symptoms. If the disease is genetic, the carrier will be heterozygous, with a [[Dominant_allele|domin..." |
No edit summary |
||
| (6 intermediate revisions by 5 users not shown) | |||
| Line 1: | Line 1: | ||
A carrier is an organism that carries a disease without showing any | A carrier is an organism that carries a disease without showing any [[Symptom|symptoms]]. If the disease is genetic, the carrier will be [[Heterozygous|heterozygous]], with a [[Dominant allele|dominant]], healthy [[Allele|allele]] and a [[Recessive alleles|reccessive allele]] for the [[Disease|disease]] state. In the event of two carriers mating, there is a 25% chance their offspring will be affected by the disease, 50% chance of the offspring being carriers or a 25% chance of the offspring being healthy and not a carrier<ref>D.L. Hartl, E.W.Jones.(2000)Genetics: analysis of genes and genomes, 5th edition. Sudbury, Jones and Bartlett publishers</ref>. | ||
An example of this is [[ | An example of this is [[Cystic Fibrosis|Cystic Fibrosis]], where 1 in 25 of the white population are carriers of the CF gene, showing no signs of having CF themselves. | ||
A Punnett Square showing two carriers mating: (H is healthy, dominant allele, | A [[Punnett Square|Punnett Square]] showing two carriers mating: (H is healthy, [[Dominant allele|dominant allele]], he is [[Recessive alleles|recessive]] for disease state) indicates how alleles from each parent cross. | ||
{| | {| cellspacing="1" cellpadding="1" width="200" border="1" | ||
|- | |- | ||
| | | | ||
| H | | H | ||
| h | | h | ||
|- | |- | ||
| H | | H | ||
| HH | | HH | ||
| Hh | | Hh | ||
|- | |- | ||
| h | | h | ||
| Hh | | Hh | ||
| hh | | hh | ||
|} | |} | ||
==== References ==== | |||
<references /> | |||
Latest revision as of 08:34, 5 December 2017
A carrier is an organism that carries a disease without showing any symptoms. If the disease is genetic, the carrier will be heterozygous, with a dominant, healthy allele and a reccessive allele for the disease state. In the event of two carriers mating, there is a 25% chance their offspring will be affected by the disease, 50% chance of the offspring being carriers or a 25% chance of the offspring being healthy and not a carrier[1].
An example of this is Cystic Fibrosis, where 1 in 25 of the white population are carriers of the CF gene, showing no signs of having CF themselves.
A Punnett Square showing two carriers mating: (H is healthy, dominant allele, he is recessive for disease state) indicates how alleles from each parent cross.
| H | h | |
| H | HH | Hh |
| h | Hh | hh |
References
- ↑ D.L. Hartl, E.W.Jones.(2000)Genetics: analysis of genes and genomes, 5th edition. Sudbury, Jones and Bartlett publishers