Epistasis: Difference between revisions
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Epistasis is | Epistasis is an interaction in which the [[Genotype|genotype]] at one locus will mask/suppress the [[Phenotypic expression|phenotypic expression]] of the [[Genotype|genotype]] at another [[Locus|locus]]<ref>Daniel L. Hartl, Maryellen Ruvolo, (2012) Genetic:s analysis of genes and genomes, 8th edition, Burlington, Massachusetts: Jones and Bartlett Learning</ref>. | ||
An example of epistasis occurs in Labrador Retriever coat colour. Coat colour of Labrador | An example of epistasis occurs in Labrador Retriever coat colour. Coat colour of Labrador Retrievers is determined by two genes: the B gene and the E gene and the [[Phenotypes|phenotypes]] can be either black coats, chocolate brown coats or yellow coats. A [[Dominant|dominant]] B and a dominant E gene present in the genotype (e.g. BBEE, BBEe, BbEE, BbEe) will give a Labrador with a black coat, a dominant E gene present with [[Recessive allele|recessive]] B genes (e.g. bbEe, bbEE) will give Labradors with a chocolate brown coats. However, the [[Genotype|genotype]] of recessive E (e) is recessive but also epistatic in [[Homozygous|homozygous]] form (ee) so if the genotype 'ee' is present the Labrador will have a yellow coat, regardless of the B gene genotype. This is an example of epistasis as the genotype at the E gene determines the expression of the B gene<ref>https://online.science.psu.edu/biol011_sandbox_7239/node/7371</ref>. | ||
=== Refereneces === | |||
<references / | <references /> | ||
Latest revision as of 17:18, 24 October 2017
Epistasis is an interaction in which the genotype at one locus will mask/suppress the phenotypic expression of the genotype at another locus[1].
An example of epistasis occurs in Labrador Retriever coat colour. Coat colour of Labrador Retrievers is determined by two genes: the B gene and the E gene and the phenotypes can be either black coats, chocolate brown coats or yellow coats. A dominant B and a dominant E gene present in the genotype (e.g. BBEE, BBEe, BbEE, BbEe) will give a Labrador with a black coat, a dominant E gene present with recessive B genes (e.g. bbEe, bbEE) will give Labradors with a chocolate brown coats. However, the genotype of recessive E (e) is recessive but also epistatic in homozygous form (ee) so if the genotype 'ee' is present the Labrador will have a yellow coat, regardless of the B gene genotype. This is an example of epistasis as the genotype at the E gene determines the expression of the B gene[2].
Refereneces
- ↑ Daniel L. Hartl, Maryellen Ruvolo, (2012) Genetic:s analysis of genes and genomes, 8th edition, Burlington, Massachusetts: Jones and Bartlett Learning
- ↑ https://online.science.psu.edu/biol011_sandbox_7239/node/7371