Presynaptic neurone: Difference between revisions

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filled in empty page on presynaptic neurones. quick definition and brief description of mechanism
 
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Added the references correctly, that is, I added them as explained in the lecture.
 
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 The presynaptic neurone is the neurone that releases [[Neurotransmitter|neurotransmitter]], across the synapse, to the [[Postsynaptic neurone|post synaptic neurone]].  
The presynaptic neurone is a neuron from the axon terminal of which an electrical impulse is transmitted across a synaptic cleft to the cell body or one or more dendrites of a postsynaptic neuron by the release of a chemical neurotransmitter; an example is acetylcholine.  


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When an [[Action potential|action potential arrives]] at the [[Axon terminal|axon terminal]] of the presynaptic membrane, [[Calcium ion channel|Ca<sup>2+</sup> ion channels]] open, allowing the ions to move into the cell down their [[Concentration Gradient|concentration gradient]]. This, in turn, causes the neurotransmitter containing [[Vesicles|vesicles]] to translocate and fuse to the [[Presynaptic membrane|presynaptic membrane]]. The neurotransmitter diffuses across the synapse and starts a new action potential in the postsynaptic neurone<ref>https://medical-dictionary.thefreedictionary.com/presynaptic+neuron</ref>.


When an [[Action potential|action potential arrives]] at the [[Axon terminal|axon terminal]] of the presynaptic membrane, Ca2+ ion channels open, allowing the ions to move into the cell down their [[Concentration Gradient|concentration gradient]]. This in turn causes the neurotransmitter containing [[Vesicles|vesicles]] to translocate and fuse to the [[Presynaptic membrane|presynaptic membrane]]. The neurotransmitter diffuses across the synapse and starts a new action potential in the post synaptic neurone.
=== Reference ===


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Latest revision as of 08:36, 6 December 2017

The presynaptic neurone is a neuron from the axon terminal of which an electrical impulse is transmitted across a synaptic cleft to the cell body or one or more dendrites of a postsynaptic neuron by the release of a chemical neurotransmitter; an example is acetylcholine.

When an action potential arrives at the axon terminal of the presynaptic membrane, Ca2+ ion channels open, allowing the ions to move into the cell down their concentration gradient. This, in turn, causes the neurotransmitter containing vesicles to translocate and fuse to the presynaptic membrane. The neurotransmitter diffuses across the synapse and starts a new action potential in the postsynaptic neurone[1].

Reference