Clonal selection: Difference between revisions
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Clonal selection gives rise to a diverse of unique [[Antigen receptor|antigen receptors]]. However, self-recognising receptors are made as well. If native antigens i.e. on a tissue surface is recognised, [[Antigen|antigen]] could bind and attack native [[Organs|organs]]. That's why [[Clonal Deletion|Clonal Deletion]] is important as during the development of [[Lymphocytes|lymphocytes]], these self-reacting antigen receptors are removed before they can mature<ref>(1) K. Murphy, C. Weaver. Janeway's Immunobiology; 9th Edition; Garland Science, Taylor and Francis Group, LLC; 15-16p.</ref>. | |||
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Latest revision as of 17:03, 23 October 2018
Clonal selection gives rise to a diverse of unique antigen receptors. However, self-recognising receptors are made as well. If native antigens i.e. on a tissue surface is recognised, antigen could bind and attack native organs. That's why Clonal Deletion is important as during the development of lymphocytes, these self-reacting antigen receptors are removed before they can mature[1].
References
- ↑ (1) K. Murphy, C. Weaver. Janeway's Immunobiology; 9th Edition; Garland Science, Taylor and Francis Group, LLC; 15-16p.