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'''Guanosine diphosphate (GDP)''' | '''Guanosine diphosphate (GDP)''' | ||
<br> Molecular formula: C<sub>10</sub>H<sub>15</sub>N<sub>5</sub>O<sub>11</sub>P<sub>2</sub><ref>http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=8977#x304</ref> | |||
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Guanosine diphosphate is a product of the [[Dephosphorylation|dephosphorylation]] of guanosine triphosphate ([[GTP|GTP]]) by [[GTPase|GTPases]] | Guanosine diphosphate is a [[Purine|purine]] [[Nucleoside|nucleoside]] diphosphate, and is a product of the [[Dephosphorylation|dephosphorylation]] of guanosine triphosphate ([[GTP|GTP]]) by [[GTPase|GTPases]]. The conversion of GTP to GDP (and vice versa) has a physiological involvment in [[G-proteins|G-Protein]] signal transduction, whereby the [[G-proteins|G-Protein]] exchanges it's bound GDP for [[GTP|GTP]], leaving it in an active state. In order for the conversion GDP to [[GTP|GTP]] to take place, the enzymes [[Pyruvate kinase|pyruvate kinase]] and [[Phosphoenolpyruvate|phosphoenolpyruvate]] are necessary.<ref>http://www.uscnk.com/directory/Guanosine-6883.htm</ref><br> | ||
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Latest revision as of 15:15, 1 November 2011
Guanosine diphosphate (GDP)
Molecular formula: C10H15N5O11P2[1]
Guanosine diphosphate is a purine nucleoside diphosphate, and is a product of the dephosphorylation of guanosine triphosphate (GTP) by GTPases. The conversion of GTP to GDP (and vice versa) has a physiological involvment in G-Protein signal transduction, whereby the G-Protein exchanges it's bound GDP for GTP, leaving it in an active state. In order for the conversion GDP to GTP to take place, the enzymes pyruvate kinase and phosphoenolpyruvate are necessary.[2]