Thymus: Difference between revisions

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The thymus is a bilobed primary lymphatic organ that gets smaller with age, until it is largely replaced by adipose tissue in elderly people <ref>Shier D., Butler J. and Lewis R. (2010); Hole's human anatomy and physiology; 12th edition; McGraw Hill; pg 512, 623</ref>. The thymus, apart from its role as a primary lymphatic organ, has some endocrine function due to 2 families of [[protein|protein]], [[thymosin|thymosin]] and [[thymopoetin|thymopoetin]], which play a critical role in the immune system, they are thought to stimulate the maturation of T cells <ref>Silverthorn D.U. (2010); Human Physiology An Integrated Approach;6th edition; Pearson; pg 819 Patton K.T., Thibodeau G.A. (2010); Anthony's Textbook of Anatomy and Physiology; 19th edition; mosby elsevier; 567-568, 714-715</ref>.


== '''Introduction''' ==
=== '''Location''' ===


The thymus is a bilobed primary lymphatic organ that gets smaller with age, until it is largely replaced by adipose tissue in elderly people (Shier et al, 2010). The thymus, apart from its role as a primary lymphatic organ, has some endocrine function due to 2 families of protein, thymosin and thymopoetin, which play a critical role in the immune system, they are thought to stimulate the maturation of T cells (Silverthorn, 2010).
The thymus lies in the mediastinum, behind the sterum, above the [[heart|heart]]. It lies between the [[lungs|lungs]]. It extends from the root of the neck to the pericardium.  


== '''Location''' ==
=== '''Structure''' ===


The thymus lies in the [mediastinum] , behind the [sterum][http://www.example.com link title], above the heart. It lies between the lungs. It extends from the root of the neck to the pericardium (Shier, 2012).
the thymus is a soft bi-lobed lymphatic organ, enclosed in a connective tissue capsule. each lobe consists of a dense cellular cortex and a medulla. both cortex and medulla are enclosed in an [[Epithelial|epithelial]] framework different from other connective tissue frameworks seen in other lymphoid organs.  


== '''Structure''' ==
=== '''Function''' ===


the thymus is a soft bi-lobed lymphatic organ, enclosed in a connective tissue capsule (Shier et al, 2010). each lobe consists of a dense cellular cortex and a medulla. both cortex and medulla are enclosed in an epithelial framework different from other connective tissue frameworks seen in other lymphoid organs (Silverthorn, 2010).
The thymus serves as the final site for [[lymphocyte|lymphocyte]] development before birth. (2)The thymus secretes hormones that enable [[T-lymphocytes|T-lymphocytes]] mature into T-cells, so it plays an important role in the lymphatic system <ref>Shier D., Butler J. and Lewis R. (2010); Hole's human anatomy and physiology; 12th edition; McGraw Hill; pg 512, 623</ref>.  


== '''Function''' ==
=== '''Reference''' ===


(1)The thymus serves as the final site for lymphocyte development before birth.
<references /><br>
(2)The thymus secretes hormones that enable T-lymphocytes mature into T-cells, so it plays an important role in the lymphatic system.
 
== '''Reference''' ==
Shier D., Butler J. and Lewis R. (2010); Hole's human anatomy and physiology; 12th edition; McGraw Hill; pg 512, 623
Silverthorn D.U. (2010); Human Physiology An Integrated Approach;6th edition; Pearson; pg 819
Patton K.T., Thibodeau G.A. (2010); Anthony's Textbook of Anatomy and Physiology; 19th edition;
mosby elsevier; 567-568, 714-715

Latest revision as of 16:34, 30 November 2012

The thymus is a bilobed primary lymphatic organ that gets smaller with age, until it is largely replaced by adipose tissue in elderly people [1]. The thymus, apart from its role as a primary lymphatic organ, has some endocrine function due to 2 families of protein, thymosin and thymopoetin, which play a critical role in the immune system, they are thought to stimulate the maturation of T cells [2].

Location

The thymus lies in the mediastinum, behind the sterum, above the heart. It lies between the lungs. It extends from the root of the neck to the pericardium.

Structure

the thymus is a soft bi-lobed lymphatic organ, enclosed in a connective tissue capsule. each lobe consists of a dense cellular cortex and a medulla. both cortex and medulla are enclosed in an epithelial framework different from other connective tissue frameworks seen in other lymphoid organs.

Function

The thymus serves as the final site for lymphocyte development before birth. (2)The thymus secretes hormones that enable T-lymphocytes mature into T-cells, so it plays an important role in the lymphatic system [3].

Reference

  1. Shier D., Butler J. and Lewis R. (2010); Hole's human anatomy and physiology; 12th edition; McGraw Hill; pg 512, 623
  2. Silverthorn D.U. (2010); Human Physiology An Integrated Approach;6th edition; Pearson; pg 819 Patton K.T., Thibodeau G.A. (2010); Anthony's Textbook of Anatomy and Physiology; 19th edition; mosby elsevier; 567-568, 714-715
  3. Shier D., Butler J. and Lewis R. (2010); Hole's human anatomy and physiology; 12th edition; McGraw Hill; pg 512, 623