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'''Allergic Reaction'''
<span style="line-height: 1.5em">An allergic reaction is a hypersensitivity disorder of the </span>[[Immune system]]<span style="line-height: 1.5em">. They occur when a persons immune system reacts to harmless substances. They are caused by excessive activation of two&nbsp;types of&nbsp;</span>[[White blood cells]]<span style="line-height: 1.5em">; </span>[[Basophils]]<span style="line-height: 1.5em"> and </span>[[Mast cells]]<span style="line-height: 1.5em">. These cells are activated by a&nbsp;type of antibody called </span>[[Immunoglobulin E]]<span style="line-height: 1.5em"> (IgE), which results in an inflammatory response&nbsp;</span><ref name="[1]">Kay AB (2000). "Overview of 'allergy and allergic diseases: with a view to the future'". Br. Med. Bull. 56 (4): 843–64. doi:10.1258/0007142001903481. PMID 11359624.</ref>.


An allergic reaction is a hypersensitivity disorder of the [[Immune system]]. They occur when a persons immune system reacts to harmless substances. They are caused by excessive activation of two&nbsp;types of&nbsp;[[White blood cells]]; [[Basophils]] and [[Mast cells]]. These cells are activated by a&nbsp;type of antibody called [[Immunoglobulin E]] (IgE), which results in an inflammatory response. <ref name="[1]">Kay AB (2000). "Overview of 'allergy and allergic diseases: with a view to the future'". Br. Med. Bull. 56 (4): 843–64. doi:10.1258/0007142001903481. PMID 11359624.</ref>
One of the most common allergies in the UK is peanut allergy.&nbsp; Upon ingestion, a spectrum of allergic symptoms from mild up to life threatening anaphylaxis can be experienced.&nbsp; Trials carried out in Addenbrooke's Hospital in Cambridge in 2014&nbsp;have been seemingly successful, with up to 84% of participants - all children - able to consume the equivalent of 5 whole peanuts by completion.


'''References'''
=== References ===


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Latest revision as of 14:19, 18 October 2016

An allergic reaction is a hypersensitivity disorder of the Immune system. They occur when a persons immune system reacts to harmless substances. They are caused by excessive activation of two types of White blood cells; Basophils and Mast cells. These cells are activated by a type of antibody called Immunoglobulin E (IgE), which results in an inflammatory response [1].

One of the most common allergies in the UK is peanut allergy.  Upon ingestion, a spectrum of allergic symptoms from mild up to life threatening anaphylaxis can be experienced.  Trials carried out in Addenbrooke's Hospital in Cambridge in 2014 have been seemingly successful, with up to 84% of participants - all children - able to consume the equivalent of 5 whole peanuts by completion.

References

  1. Kay AB (2000). "Overview of 'allergy and allergic diseases: with a view to the future'". Br. Med. Bull. 56 (4): 843–64. doi:10.1258/0007142001903481. PMID 11359624.