Penetrance: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
Minor typo correction. |
||
| (6 intermediate revisions by 5 users not shown) | |||
| Line 1: | Line 1: | ||
Penetrance is the percentage of the expression of the [[Phenotype|phenotype]] in an [[Organism|organism]] from its adjacent [[Genotype|genotype]] <ref>Hartl, D.L., Ruvolo, M. (2012) Genetics:Analysis Of Genes And Genomes, United States of America: Jones and Bartlett</ref> (e.g. how many members of a [[Population|population]] with a specific genotype that show the expected phenotype). | |||
== | An example of complete pentrance is [[Neurofibromatosis type 1|neurofibromatosis type I]]. The symptoms of this mutation will be shown in all of the mutants - 100% penetrance. <ref>NHS. (ND). Penetrance. Available at: http://www.geneticseducation.nhs.uk/genetic-glossary/221-penetrance (Accessed at: 26/11/14)</ref> | ||
Incomplete penetrance is when some individuals with a particular (dominant) mutation express a wild type phenotype. An example is [[Polydactyly|polydactyly]]. | |||
=== Reference === | |||
<references /> | <references /> | ||
Latest revision as of 08:29, 28 November 2016
Penetrance is the percentage of the expression of the phenotype in an organism from its adjacent genotype [1] (e.g. how many members of a population with a specific genotype that show the expected phenotype).
An example of complete pentrance is neurofibromatosis type I. The symptoms of this mutation will be shown in all of the mutants - 100% penetrance. [2]
Incomplete penetrance is when some individuals with a particular (dominant) mutation express a wild type phenotype. An example is polydactyly.
Reference
- ↑ Hartl, D.L., Ruvolo, M. (2012) Genetics:Analysis Of Genes And Genomes, United States of America: Jones and Bartlett
- ↑ NHS. (ND). Penetrance. Available at: http://www.geneticseducation.nhs.uk/genetic-glossary/221-penetrance (Accessed at: 26/11/14)