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A carrier is an organism that carries a disease without showing any signs or symptoms. If the disease is genetic, the carrier will be heterozygous, with a [[ | A carrier is an organism that carries a disease without showing any signs or symptoms. If the disease is genetic, the carrier will be heterozygous, with a [[Dominant allele|dominant]], healthy [[Allele|allele]] and a [[Recessive alleles|reccessive allele]] for the disease state. In the event of two carriers mating, there is a 25% chance their offspring will be affected by the disease, 50% chance of the offspring being carriers too or a 25% chance of the offspring being healthy and not a carrier. | ||
An example of this is [[ | An example of this is [[Cystic Fibrosis|Cystic Fibrosis]], where 1 in 25 of the white population are carriers of the CF gene, showing no signs of having CF themselves. | ||
A Punnett Square showing two carriers mating: (H is healthy, dominant allele, h is recessive for disease state) | A [[Punnett Square|Punnett Square]] showing two carriers mating: (H is healthy, [[Dominant_allele|dominant allele]], h is [[Recessive_alleles|recessive]] for disease state) | ||
{| width="200" border="1" cellpadding="1" cellspacing="1" | {| width="200" border="1" cellpadding="1" cellspacing="1" | ||
|- | |- | ||
| | | | ||
| H | | H | ||
| h | | h | ||
|- | |- | ||
| H | | H | ||
| HH | | HH | ||
| Hh | | Hh | ||
|- | |- | ||
| h | | h | ||
| Hh | | Hh | ||
| hh | | hh | ||
|} | |} | ||
Revision as of 01:15, 17 October 2014
A carrier is an organism that carries a disease without showing any signs or symptoms. If the disease is genetic, the carrier will be heterozygous, with a dominant, healthy allele and a reccessive allele for the disease state. In the event of two carriers mating, there is a 25% chance their offspring will be affected by the disease, 50% chance of the offspring being carriers too or a 25% chance of the offspring being healthy and not a carrier.
An example of this is Cystic Fibrosis, where 1 in 25 of the white population are carriers of the CF gene, showing no signs of having CF themselves.
A Punnett Square showing two carriers mating: (H is healthy, dominant allele, h is recessive for disease state)
| H | h | |
| H | HH | Hh |
| h | Hh | hh |