Somatostatin: Difference between revisions

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Somatostatin is also known as GHIH, which stands for growth hormone inhibiting hormone. Another name for it is SRIF (somatotropin release-inhibiting factor) but this name is not often used.
Somatostatin is also known as GHIH, which stands for growth hormone inhibiting hormone. Another name for it is SRIF (somatotropin release-inhibiting factor) but this name is not often used.  


Somatostatin is a peptide [[hormone|hormone]] which regulates [[glucagon|glucagon]] and [[insulin|insulin]]. It stops the release of [[secondary hormones|secondary hormones]] which regulates the [[endocrine system|endocrine system]]. It is secreted in the [[Intestine|intestine]], [[Neurone|neurones]], stomach and delta cells of the pancreas. It travels through the portal blood stream until it has its effect in the digestive system and [[Anterior_pituitary_gland|anterior pituitary gland]]. It is induced by low pH  
Somatostatin is a peptide [[Hormone|hormone]] which regulates [[Glucagon|glucagon]] and [[Insulin|insulin]]. It stops the release of [[Secondary hormones|secondary hormones]] which regulates the [[Endocrine system|endocrine system]]. It is secreted in the [[Intestine|intestine]], [[Neurone|neurones]], stomach and delta cells of the pancreas. It travels through the portal blood stream until it has its effect in the digestive system and [[Anterior pituitary gland|anterior pituitary gland]]. It is induced by low pH  


Its effects include:  
Its effects include:  


*inhibits the release of GH, [[adenylyl cyclase|adenylyl cyclase]], [[prolactin|prolactin]] and TSH in the anterior pituitary gland  
*inhibits the release of GH, [[Adenylyl cyclase|adenylyl cyclase]], [[Prolactin|prolactin]] and TSH in the anterior pituitary gland  
*inhibits the release of gastrin and secretin among others  
*inhibits the release of gastrin and secretin among others  
*inhibits the release of pancreate hormones i.e. insulin and glucagon which suppresses the exocrin secretory action of the [[pancreas|pancreas]]<ref>http://www.britannica.com/EBchecked/topic/553961/somatostatin, as seen on the 19th Oct 2014</ref><br>
*inhibits the release of pancreate hormones i.e. insulin and glucagon which suppresses the exocrin secretory action of the [[Pancreas|pancreas]]<ref>http://www.britannica.com/EBchecked/topic/553961/somatostatin, as seen on the 19th Oct 2014</ref>.<br>


=== References ===
=== References ===


<references />
<references />

Latest revision as of 12:24, 10 December 2018

Somatostatin is also known as GHIH, which stands for growth hormone inhibiting hormone. Another name for it is SRIF (somatotropin release-inhibiting factor) but this name is not often used.

Somatostatin is a peptide hormone which regulates glucagon and insulin. It stops the release of secondary hormones which regulates the endocrine system. It is secreted in the intestine, neurones, stomach and delta cells of the pancreas. It travels through the portal blood stream until it has its effect in the digestive system and anterior pituitary gland. It is induced by low pH

Its effects include:

  • inhibits the release of GH, adenylyl cyclase, prolactin and TSH in the anterior pituitary gland
  • inhibits the release of gastrin and secretin among others
  • inhibits the release of pancreate hormones i.e. insulin and glucagon which suppresses the exocrin secretory action of the pancreas[1].

References