Lyonization: Difference between revisions

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&nbsp;Lyonization occurs whereby only a single X chromosome is left active in the nucleus of a cell as a result of [[Dosage_Compensation_Mechanism|dosage compensation]]. So, in females (posess 2 X chromosomes) only X chromosome is active in any one cell at a time.<br>Which X chromosome becomes inactive is entirely random, and not all cells will have the same inactive X chromosome.<ref>http://nfed.org/uploads/Lyonization.pdf</ref><span style="line-height: 1.5em;">&nbsp;During development, one of the X chromosomes is randomly made inactive, and so the progeny cells also have the same X chromosome inactive. As a result of this, defferent </span>[[Alleles|alleles&nbsp;]]<span style="line-height: 1.5em;">that are carried on the X chromosome are expressed in different areas of the female body.</span>
Lyonization occurs whereby only a single [[X chromosome|X chromosome]] is left active in the nucleus of a cell as a result of [[Dosage Compensation Mechanism|dosage compensation]]. So, in females (posess 2 X chromosomes) only X chromosome is active in any one cell at a time.


References
Which X chromosome becomes inactive is entirely random, and not all cells will have the same inactive X chromosome.<ref>http://nfed.org/uploads/Lyonization.pdf</ref><span style="line-height: 1.5em;">&nbsp;During development, one of the X chromosomes is randomly made inactive, and so the progeny cells also have the same X chromosome inactive. As a result of this, defferent </span>[[Alleles|alleles]]&nbsp;<span style="line-height: 1.5em;">that are carried on the X chromosome are expressed in different areas of the female body.</span>
 
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Revision as of 23:25, 26 November 2014

Lyonization occurs whereby only a single X chromosome is left active in the nucleus of a cell as a result of dosage compensation. So, in females (posess 2 X chromosomes) only X chromosome is active in any one cell at a time.

Which X chromosome becomes inactive is entirely random, and not all cells will have the same inactive X chromosome.[1] During development, one of the X chromosomes is randomly made inactive, and so the progeny cells also have the same X chromosome inactive. As a result of this, defferent alleles that are carried on the X chromosome are expressed in different areas of the female body.

References