Patau syndrome: Difference between revisions
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=== Life expectancy === | === Life expectancy === | ||
45% of those born with Patau Syndrome die with one month and 70% within the first 6 <ref>http://emedicine.medscape.com/article/947706-overview</ref>. | 45% of those born with Patau Syndrome die with one month and 70% within the first 6 <ref>http://emedicine.medscape.com/article/947706-overview</ref>. The median survival age for patient is about 2.5 days in the United States<ref>http://syndrome.org/patau-syndrome/</ref>. | ||
=== References === | === References === | ||
<references /><br> | <references /><br> | ||
Revision as of 01:39, 20 October 2016
Patau Syndrome /ˈpætaʊ/ is also known as Trisomy 13 as it is caused by an extra chromosome 13. This is similar to the more well-known Down's syndrome, except that the trisomy occurs on chromosome 21. Patau is the least common non-lethal trisomies, affecting 1 in 10,000 live-births. Out of this 80% will have a full trisomy, with the remainder having partial trisomy (due to translocation or mosaicism)[1][2].
Symptoms
These can vary greatly, however almost all suffer from severe mental deficiency.
Physical:
- Polydactyly
- Rocker-bottom feet
- Cleft Palate (this occurs in about 60% of those with Patau Syndrome)
- Holoprosencephaly (forebrain in the embryo does not divide into two hemispheres)
- Microcephaly (small head size)
- Microphthalmia (small eyes)
- Congenital heart defect (affects around 80%)
- Seizures
Life expectancy
45% of those born with Patau Syndrome die with one month and 70% within the first 6 [3]. The median survival age for patient is about 2.5 days in the United States[4].