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CRISPR is the abbreviation of clustered regularly interspaced short [[Palindromic sequence|palindromic repeats]], which represents the [[Gene|gene]] fragments of [[Prokaryotic|prokaryotic]] [[Organism|organisms]] containing repetitive&nbsp;base sequence in a short length. The widely applied CRISPR technology is the Crispr/Cas system for gene sequence editions by transferring [[Cas9 protein|Cas9 protein]] family&nbsp;encoded gene into cells and potentially simplifies the procedure of cutting [[DNA methylation|DNA]] at a desired location&nbsp;<ref>Ledford H (3 June 2015). "CRISPR, the disruptor". News Feature. Nature 522 (7554).</ref>.<br>  
CRISPR is the abbreviation of clustered regularly interspaced short [[Palindromic sequence|palindromic repeats]], which represents the [[Gene|gene]] fragments of [[Prokaryotic|prokaryotic]] [[Organism|organisms]] containing repetitive&nbsp;base sequence in a short length. The widely applied CRISPR technology is the Crispr/Cas system for gene sequence editions by transferring [[Cas9 protein|Cas9 protein]] family&nbsp;encoded gene into cells and potentially simplifies the procedure of cutting [[DNA methylation|DNA]] at a desired location&nbsp;<ref>Ledford H (3 June 2015). "CRISPR, the disruptor". News Feature. Nature 522 (7554).</ref>.&nbsp;<br>  


The CRISPR&nbsp;technology is now being adapted in order to be used to fight disease. For example, adaptations are being made to use CRISPR to fight [[antibiotic resistance|antibiotic resistance]]. Alongside this, labs are trying to modify mosquitos to release into the wild in order to eradicate [[malaria|malaria]], however there are some ethical concerns stipulating around this.  
There are three CRISPR systems, one of which has been adapted for eukaryotes. This is the Type II CRISPR system, and it consists of three stages:
 
1) Acquisition
 
2) crRNA processing
 
3) Interference&nbsp;<br>
 
The CRISPR&nbsp;technology is now being adapted in order to be used to fight disease. For example, adaptations are being made to use CRISPR to fight [[Antibiotic resistance|antibiotic resistance]]. Alongside this, labs are trying to modify mosquitos to release into the wild in order to eradicate [[Malaria|malaria]], however there are some ethical concerns stipulating around this.  


=== Reference  ===
=== Reference  ===


<references />
<references />

Revision as of 19:05, 16 October 2017

CRISPR is the abbreviation of clustered regularly interspaced short palindromic repeats, which represents the gene fragments of prokaryotic organisms containing repetitive base sequence in a short length. The widely applied CRISPR technology is the Crispr/Cas system for gene sequence editions by transferring Cas9 protein family encoded gene into cells and potentially simplifies the procedure of cutting DNA at a desired location [1]

There are three CRISPR systems, one of which has been adapted for eukaryotes. This is the Type II CRISPR system, and it consists of three stages:

1) Acquisition

2) crRNA processing

3) Interference 

The CRISPR technology is now being adapted in order to be used to fight disease. For example, adaptations are being made to use CRISPR to fight antibiotic resistance. Alongside this, labs are trying to modify mosquitos to release into the wild in order to eradicate malaria, however there are some ethical concerns stipulating around this.

Reference

  1. Ledford H (3 June 2015). "CRISPR, the disruptor". News Feature. Nature 522 (7554).