Carrier: Difference between revisions
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A carrier is an organism that carries a disease without showing any | A carrier is an organism that carries a disease without showing any [[Symptom|symptoms]]. If the disease is genetic, the carrier will be [[Heterozygous|heterozygous]], with a [[Dominant allele|dominant]], healthy [[Allele|allele]] and a [[Recessive alleles|reccessive allele]] for the [[Disease|disease]] state. In the event of two carriers mating, there is a 25% chance their offspring will be affected by the disease, 50% chance of the offspring being carriers or a 25% chance of the offspring being healthy and not a carrier<ref>D.L. Hartl, E.W.Jones.(2000)Genetics:analysis of genes and genomes, 5th edition. Sudbury, Jones and Bartlett publishers</ref>. | ||
An example of this is [[Cystic Fibrosis|Cystic Fibrosis]], where 1 in 25 of the white population are carriers of the CF gene, showing no signs of having CF themselves. | An example of this is [[Cystic Fibrosis|Cystic Fibrosis]], where 1 in 25 of the white population are carriers of the CF gene, showing no signs of having CF themselves. | ||
A [[Punnett Square|Punnett Square]] showing two carriers mating: (H is healthy, [[Dominant allele|dominant allele]], h is [[Recessive alleles|recessive]] for disease state) | A [[Punnett Square|Punnett Square]] showing two carriers mating: (H is healthy, [[Dominant allele|dominant allele]], h is [[Recessive alleles|recessive]] for disease state) indicates how alleles from each parent cross. | ||
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==== References ==== | |||
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Revision as of 11:53, 4 December 2017
A carrier is an organism that carries a disease without showing any symptoms. If the disease is genetic, the carrier will be heterozygous, with a dominant, healthy allele and a reccessive allele for the disease state. In the event of two carriers mating, there is a 25% chance their offspring will be affected by the disease, 50% chance of the offspring being carriers or a 25% chance of the offspring being healthy and not a carrier[1].
An example of this is Cystic Fibrosis, where 1 in 25 of the white population are carriers of the CF gene, showing no signs of having CF themselves.
A Punnett Square showing two carriers mating: (H is healthy, dominant allele, h is recessive for disease state) indicates how alleles from each parent cross.
| H | h | |
| H | HH | Hh |
| h | Hh | hh |
References
- ↑ D.L. Hartl, E.W.Jones.(2000)Genetics:analysis of genes and genomes, 5th edition. Sudbury, Jones and Bartlett publishers