Conformational change: Difference between revisions

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<h2> Definition  </h2>
Conformational change a change in shape of [[Macromolecules|macromolecule]] due to the change in external or environmental factors.  
<p>Is a change in shape of macromolecule due to the change in external or environmental factors.  
 
</p><p>Macromolecules are flexible thus it can change its shape in response to different factors.  
Macromolecules are flexible thus it can change its shape in response to different factors<ref>https://en.wikipedia.org/wiki/Conformational_change</ref>.
</p><p>In biochemistry module, the most common example for conformational change would be G-protein and different type of enzyme.  
 
</p>
In biochemistry module, the most common example for conformational change would be G-protein and different type of enzyme.  
<h5> Typical Factors that could induce conformational change:&#160</h5>
 
<p>i. temperature  
=== Typical Factors that could induce conformational change:&nbsp===
</p><p>ii. pH value  
 
</p><p>iii. presence of inhibitor/ligand (especially in enzyme)<br /> iv. mutation&#160;<br />
*temperature
</p>
*pH value
<h6> Example of conformational change (in enzyme)  </h6>
*presence of inhibitor/ligand (especially in enzyme)
<p><a href="https://www.google.com/search?q=conformational+change&amp;espv=2&amp;biw=1366&amp;bih=662&amp;source=lnms&amp;tbm=isch&amp;sa=X&amp;ved=0ahUKEwiDo_ut9NrQAhVKtJQKHcTQBEwQ_AUIBigB#tbm=isch&amp;q=conformational+change+enzyme&amp;imgrc=qfRthAd5AkzARM%3A">www.google.com/search</a>
*mutation&nbsp;<br>
</p>
 
<h6> References  </h6>
=== References ===
<p>https://en.wikipedia.org/wiki/Conformational_change
 
</p>
<references /><br>

Revision as of 17:19, 4 December 2016

Conformational change a change in shape of macromolecule due to the change in external or environmental factors.

Macromolecules are flexible thus it can change its shape in response to different factors[1].

In biochemistry module, the most common example for conformational change would be G-protein and different type of enzyme.

Typical Factors that could induce conformational change: 

  • temperature
  • pH value
  • presence of inhibitor/ligand (especially in enzyme)
  • mutation 

References