Penicilllin: Difference between revisions
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Penicillin is an [[Antibiotic|antibiotic]] that is used to treat [[Bacterial infection|bacterial infections]]. Penicillin kills susceptible [[Bacteria|bacteria]] by specifically inhibiting the [[Transpeptidase|transpeptidase]] that catalyzes the final step in [[Cell wall|cell wall]] biosynthesis, the [[Cross linking|cross-linking]] of [[Peptidoglycan|peptidoglycan]]<ref>The Journal of Biological Chemistry. Vol.255, No 9, issue of May 10, pp. 3977-3986, 1980</ref>. | Penicillin is an [[Antibiotic|antibiotic]] that is used to treat [[Bacterial infection|bacterial infections]]. Penicillin kills susceptible [[Bacteria|bacteria]] by specifically inhibiting the [[Transpeptidase|transpeptidase]] that catalyzes the final step in [[Cell wall|cell wall]] biosynthesis, the [[Cross linking|cross-linking]] of [[Peptidoglycan|peptidoglycan]]<ref>The Journal of Biological Chemistry. Vol.255, No 9, issue of May 10, pp. 3977-3986, 1980</ref><ref>M.Lobanovoska and G.Pilla. Penicillin's discovery and Antibiotic resistance: Lessons for the future? Yale J Biol Med 2017 Mar, 90(1): 135-145</ref>. | ||
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Revision as of 12:16, 17 October 2018
Penicillin is an antibiotic that is used to treat bacterial infections. Penicillin kills susceptible bacteria by specifically inhibiting the transpeptidase that catalyzes the final step in cell wall biosynthesis, the cross-linking of peptidoglycan[1][2].