Peptide bonds: Difference between revisions
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A peptide bond is a kind of linkage between two amino acids. It is also known as an amide bond. A peptide bond connects two amino acids, forming a dipeptide, and is associated with the loss of a water molecule. This process is called a condensation reaction. One perhaps surprising fact about peptide bonds is that they are very kinetically stable, in fact a peptide bond in a solution will last 1000 years, if no catalyst is present to disrupt it. | A peptide bond is a kind of linkage between two [[Amino_acids|amino acids]]. It is also known as an [[Amide bond|amide bond]]. A [[Peptide_bond|peptide bond]] connects two [[Amino_acids|amino acids]], forming a dipeptide, and is associated with the loss of a water molecule. This process is called a [[Condensation reaction|condensation reaction]]. One perhaps surprising fact about peptide bonds is that they are very kinetically stable, in fact a peptide bond in a solution will last 1000 years, if no catalyst is present to disrupt it. | ||
Many amino acids can be connected via peptide bonds, making a polypeptide. Each amino acid is then called a residue as it forms part of the polypeptide | Many [[Amino_acids|amino acids]] can be connected via peptide bonds, making a [[Polypeptide|polypeptide]]. Each amino acid is then called a residue as it forms part of the [[Polypeptide|polypeptide]] <ref>Berg, Tymoczko, Stryer, Biochemistry 6th ed, W.H. Freeman and Company, 2007</ref>. The ends of a [[Polypeptide|polypeptide]] chain will be different because an alpha amino group is present at one end and an [[Alpha carboxyl group|alpha carboxyl group]] present at the other. This gives the polypeptide chain polarity <ref>Alberts, Johnson, Lewis, Raff, Roberts, Walter. Molecular Biology of The Cell 2008, Garland Science.</ref>. | ||
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Revision as of 09:09, 7 January 2011
A peptide bond is a kind of linkage between two amino acids. It is also known as an amide bond. A peptide bond connects two amino acids, forming a dipeptide, and is associated with the loss of a water molecule. This process is called a condensation reaction. One perhaps surprising fact about peptide bonds is that they are very kinetically stable, in fact a peptide bond in a solution will last 1000 years, if no catalyst is present to disrupt it.
Many amino acids can be connected via peptide bonds, making a polypeptide. Each amino acid is then called a residue as it forms part of the polypeptide [1]. The ends of a polypeptide chain will be different because an alpha amino group is present at one end and an alpha carboxyl group present at the other. This gives the polypeptide chain polarity [2].