Lysosyme: Difference between revisions
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Lysozyme is an enzyme with antibacterial properties. |
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Lysozymes are [[Enzymes|enzymes]] which inhibit or destroy the growth of bacteria by breaking down the [[Carbohydrate]] content of their cell walls. Therefore lysozyme can be said to be a part of the immune system. It is present in birds, mammals and insects<ref>Worthington Biomedical Corporation, (2011). Lysozyme. http://www.worthington-biochem.com/ly/default.html.(last veiwed, 1/12/2011).</ref> | Lysozymes are [[Enzymes|enzymes]] which inhibit or destroy the growth of bacteria by breaking down the [[Carbohydrate]] content of their cell walls. Therefore lysozyme can be said to be a part of the immune system. It is present in birds, mammals and insects<ref name="1">Worthington Biomedical Corporation, (2011). Lysozyme. http://www.worthington-biochem.com/ly/default.html.(last veiwed, 1/12/2011).</ref> | ||
=== Uses of lysozyme === | === Uses of lysozyme === | ||
Lysozyme is very useful in molecular biology because of its ability to perform cell lysis which is an essential process in the extraction of [[Recombinant DNA|recombinant DNA.]]<ref>Invitra, (n.d). What is lysozyme?.http://www.invitria.com/products-and-services/lysozyme.html. (last veiwed, 1/12/2011).</ref> | Lysozyme is very useful in molecular biology because of its ability to perform cell lysis which is an essential process in the extraction of [[Recombinant DNA|recombinant DNA.]]<ref name="2">Invitra, (n.d). What is lysozyme?.http://www.invitria.com/products-and-services/lysozyme.html. (last veiwed, 1/12/2011).</ref> | ||
It also protects against infection from viruses as well as prevent yeast or fungal invation of regions containing mucus. <ref>Invitro,(n.d). what is lysozyme? http://www.invitria.com/products-and-services/lysozyme.html. (last viewed, 1/12/2011).</ref> | It also protects against infection from viruses as well as prevent yeast or fungal invation of regions containing mucus. <ref name="2">Invitro,(n.d). what is lysozyme? http://www.invitria.com/products-and-services/lysozyme.html. (last viewed, 1/12/2011).</ref> | ||
=== History === | === History === | ||
Lysozyme was first discovered to be in chicken eggs in 1909 by Laschtschenko. In 1919 Bloomfield discovered that the enzyme is also present in [[Saliva|saliva]]. Its structure was determined in 1965 by Blake et.al and in 1966,its functional pathway was explained.<ref>Worthington Biochemical Corporation,(2011).Lysozyme.http://www.worthington-biochem.com/ly/default.html.(last viewed, 1/12/2011).</ref> | Lysozyme was first discovered to be in chicken eggs in 1909 by Laschtschenko. In 1919 Bloomfield discovered that the enzyme is also present in [[Saliva|saliva]]. Its structure was determined in 1965 by Blake et.al and in 1966,its functional pathway was explained.<ref name="1">Worthington Biochemical Corporation,(2011).Lysozyme.http://www.worthington-biochem.com/ly/default.html.(last viewed, 1/12/2011).</ref> | ||
=== Molecular Structure === | === Molecular Structure === | ||
Lysozyme of chicken comprises of one hundred and twenty eight amino acids. Amino acids of other bird species express a homology and only differ in 4 to 20 amino acids.This enzyme consists of an active site which divide it into two part which are joined by an [[Alpha-helix|alpha helix]].One part is made up entirely of a beta sheet structure and the other part is made up of a helix.<ref>Worthington Biomedical Corporation,(2011). Lysozyme. http://www.worthington-biochem.com/ly/default.html. (last viewed, 1/12/2011).</ref> | Lysozyme of chicken comprises of one hundred and twenty eight amino acids. Amino acids of other bird species express a homology and only differ in 4 to 20 amino acids.This enzyme consists of an active site which divide it into two part which are joined by an [[Alpha-helix|alpha helix]].One part is made up entirely of a beta sheet structure and the other part is made up of a helix.<ref name="1">Worthington Biomedical Corporation,(2011). Lysozyme. http://www.worthington-biochem.com/ly/default.html. (last viewed, 1/12/2011).</ref> | ||
=== References === | === References === | ||
Revision as of 20:27, 1 December 2011
Lysozymes are enzymes which inhibit or destroy the growth of bacteria by breaking down the Carbohydrate content of their cell walls. Therefore lysozyme can be said to be a part of the immune system. It is present in birds, mammals and insectsCite error: Invalid <ref> tag; name cannot be a simple integer. Use a descriptive title
Uses of lysozyme
Lysozyme is very useful in molecular biology because of its ability to perform cell lysis which is an essential process in the extraction of recombinant DNA.Cite error: Invalid <ref> tag; name cannot be a simple integer. Use a descriptive title
It also protects against infection from viruses as well as prevent yeast or fungal invation of regions containing mucus. Cite error: Invalid <ref> tag; name cannot be a simple integer. Use a descriptive title
History
Lysozyme was first discovered to be in chicken eggs in 1909 by Laschtschenko. In 1919 Bloomfield discovered that the enzyme is also present in saliva. Its structure was determined in 1965 by Blake et.al and in 1966,its functional pathway was explained.Cite error: Invalid <ref> tag; name cannot be a simple integer. Use a descriptive title
Molecular Structure
Lysozyme of chicken comprises of one hundred and twenty eight amino acids. Amino acids of other bird species express a homology and only differ in 4 to 20 amino acids.This enzyme consists of an active site which divide it into two part which are joined by an alpha helix.One part is made up entirely of a beta sheet structure and the other part is made up of a helix.Cite error: Invalid <ref> tag; name cannot be a simple integer. Use a descriptive title
References
1).Invitria,(n.d), What is lysozyme?. http://www.invitria.com/products-and-services/lysozyme.html. (last viewed,1/12/2011).
2).Worthington Biochemical Corporation,(2011). Lysozyme. http://www.worthington-biochem.com/ly/default.html. (last viewed, 1/12/2011).