G-protein Coupled Receptor: Difference between revisions
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A [[Seven|seven]] [[Transmembrane|transmembrane]] spanning [[Receptor|receptor]] that interacts with [[Heterotrimeric G-proteins|G-proteins]]. [[Heterotrimeric G-proteins|G-proteins]] are composed of three subunits: alpha (α), beta (β) and gamma (γ). In the inactive state, the α subunit binds to [[GDP|GDP]], and in the active state, GDP is released and [[GTP|GTP]] binds. The α subunit disocciates from the βγ complex, and then both can activate separate effectors. | |||
Revision as of 16:45, 11 November 2010
A seven transmembrane spanning receptor that interacts with G-proteins. G-proteins are composed of three subunits: alpha (α), beta (β) and gamma (γ). In the inactive state, the α subunit binds to GDP, and in the active state, GDP is released and GTP binds. The α subunit disocciates from the βγ complex, and then both can activate separate effectors.