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When a [[Protein|protein]] is changed in shape and "unfolded", it is said to be denatured. This can occur in a number of ways, from a change in environmental factors (i.e. high/low temperature) to the addition of different chemicals (i.e. [[Solvent|solvents]]), causing breaking and changing of integral [[Bond|bonds]] within the protein. | When a [[Protein|protein]] is changed in shape and "unfolded", it is said to be denatured. This can occur in a number of ways, from a change in [[environmental factors|environmental factors]] (i.e. high/low temperature) to the addition of different chemicals (i.e. [[Solvent|solvents]]), causing breaking and changing of integral [[Bond|bonds]] within the protein. | ||
Denaturing is particularly important to consider when studying [[Enzyme|enzymes]]- If a protein's [[Enzyme active site|active site is]] changed so that it is no longer [[Complementary|complementary]] to | Denaturing is particularly important to consider when studying [[Enzyme|enzymes]]- If a protein's [[Enzyme active site|active site is]] changed so that it is no longer [[Complementary|complementary]] to its [[Substrate|substrate]] then it cannot carry out its function correctly <ref>Alberts, B. Johnson, A. Lewis, J. Raff, M. Roberts, K. Walter, P (2008). Molecular biology of the cell. 5th ed. New York: Garland Science. 130.</ref>. | ||
=== References === | === References === | ||
<references /> | <references /> | ||
<br> | <br> | ||
Revision as of 13:36, 24 October 2017
When a protein is changed in shape and "unfolded", it is said to be denatured. This can occur in a number of ways, from a change in environmental factors (i.e. high/low temperature) to the addition of different chemicals (i.e. solvents), causing breaking and changing of integral bonds within the protein.
Denaturing is particularly important to consider when studying enzymes- If a protein's active site is changed so that it is no longer complementary to its substrate then it cannot carry out its function correctly [1].
References
- ↑ Alberts, B. Johnson, A. Lewis, J. Raff, M. Roberts, K. Walter, P (2008). Molecular biology of the cell. 5th ed. New York: Garland Science. 130.