Mitogen-Activated Protein Kinase: Difference between revisions
Created page with "''' Mitogen-Activated Protein Kinases (MAPKs)''' are a family of kinases with vital roles among eukaryotes in the following cellular processes: proliferation, differentiatio..." |
No edit summary |
||
| Line 1: | Line 1: | ||
''' Mitogen-Activated Protein Kinases (MAPKs)''' are a family of kinases with vital roles among eukaryotes in the following cellular processes: proliferation, differentiation, movement, response to environmental changes, and death | ''' Mitogen-Activated Protein Kinases (MAPKs)''' are a family of kinases with vital roles among eukaryotes in the following cellular processes: proliferation, differentiation, movement, response to environmental changes, and death (Junttila MR Et. Al. (2008)). MAPKs phosphorylate and are phosphorylated on serine/threonine residues. These kinases have been observed to function in cascades starting with Mitogen-Activated Protein Kinase Kinase Kinase (MAPKKK) which phosphorylates Mitogen-Activated Protein Kinase Kinase (MAPKK) which finally phosphorylates a MAPK (Junttila MR Et. Al. (2008)). The MAPK may either directly elicite a cellular action or phosphorylate an effector protein that will elicite a cellular response (Junttila MR Et. Al. (2008)). | ||
<br> | <br> <references></references> <references />Junttila MR, Li SP, Westermarck J (2008) Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival. FASEB J. 22(4), 954–65. | ||
<references />Junttila MR, Li SP, Westermarck J (2008) Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival. FASEB J. 22(4), 954–65. | |||
Revision as of 14:02, 22 October 2012
Mitogen-Activated Protein Kinases (MAPKs) are a family of kinases with vital roles among eukaryotes in the following cellular processes: proliferation, differentiation, movement, response to environmental changes, and death (Junttila MR Et. Al. (2008)). MAPKs phosphorylate and are phosphorylated on serine/threonine residues. These kinases have been observed to function in cascades starting with Mitogen-Activated Protein Kinase Kinase Kinase (MAPKKK) which phosphorylates Mitogen-Activated Protein Kinase Kinase (MAPKK) which finally phosphorylates a MAPK (Junttila MR Et. Al. (2008)). The MAPK may either directly elicite a cellular action or phosphorylate an effector protein that will elicite a cellular response (Junttila MR Et. Al. (2008)).
Junttila MR, Li SP, Westermarck J (2008) Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival. FASEB J. 22(4), 954–65.