PI3k rbd: Difference between revisions
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< | PI3K RBD ([[PI3K|Phosoinositide 3-kinase]] [[Ras Binding domain|Ras Binding domain]]), is a domain found in [[PI3K|PI3K]] molecules that binds to the [[Ras|Ras]] protein which is key to intracellular signalling. Activated Ras will bind to p110 subunit activating PI3K alpha. To a lesser extent Ras will also activate PY3K gamma <ref>RAS binding domain(Author unknown) http://www.mrc-lmb.cam.ac.uk/rlw/text/pi3k%20web%20pages/rbd.html. Accessed 24/10/2012.</ref>. | ||
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Revision as of 18:30, 24 October 2012
PI3K RBD (Phosoinositide 3-kinase Ras Binding domain), is a domain found in PI3K molecules that binds to the Ras protein which is key to intracellular signalling. Activated Ras will bind to p110 subunit activating PI3K alpha. To a lesser extent Ras will also activate PY3K gamma [1].
References
- ↑ RAS binding domain(Author unknown) http://www.mrc-lmb.cam.ac.uk/rlw/text/pi3k%20web%20pages/rbd.html. Accessed 24/10/2012.