Chromosome 13: Difference between revisions

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Chromosome 13 is&nbsp;one of 22 [https://teaching.ncl.ac.uk/bms/wiki/index.php/Autosomal_chromosomes automsomal]&nbsp;pairs of chromosomes found in humans. It is&nbsp;thought to contain&nbsp;about&nbsp;114 million&nbsp;base pairs&nbsp;and codes for between 600 and 700 genes which code&nbsp;for&nbsp;various things from ATPase to specific diseases.&nbsp;It is widely associated breast cancer; gene BRCA2 and some&nbsp;bladder cancers as well as Wilson's disease which&nbsp;is a mutation of the&nbsp;ATP7B gene. &nbsp;<br>There are also many chromosomal conditions associated with chromosome 13 including [[Patau_Syndrome|Patau syndrome]] which is [[Trisomy|trisomy]] of chromosome 13 and [[Retinoblastoma|Retinoblastoma]]&nbsp;which can be caused by&nbsp;deletion of a specific region (13q14) containing the RB1 gene.
Chromosome 13 is&nbsp;one of 22 [[automsomal|automsomal]]&nbsp;pairs of chromosomes found in humans. It is&nbsp;thought to contain&nbsp;about&nbsp;114 million&nbsp;base pairs&nbsp;and codes for between 600 and 700 [[genes|genes]] which code&nbsp;for&nbsp;various things from ATPase to specific diseases.&nbsp;It is widely associated breast cancer; gene [[BRCA2|BRCA2]] and some&nbsp;bladder cancers as well as [[Wilson's disease|Wilson's disease]] which&nbsp;is a mutation of the&nbsp;[[ATP7B|ATP7B]] gene. &nbsp;


There are also many chromosomal conditions associated with chromosome 13 including [[Patau Syndrome|Patau syndrome]] which is [[Trisomy|trisomy]] of chromosome 13 and [[Retinoblastoma|Retinoblastoma]]&nbsp;which can be caused by&nbsp;deletion of a specific region (13q14) containing the RB1 gene <ref>Genetics Home Reference (2012) 'chromosome 13' http://ghr.nlm.nih.gov/chromosome/13#resources</ref><ref>Atlas Genetics Oncology (2012) 'chromosome 13' http://atlasgeneticsoncology.org/Indexbychrom/idxa_13.html</ref>.


'''References:<br>'''Genetics Home Reference (2012) 'chromosome 13' [http://ghr.nlm.nih.gov/chromosome/13#resources http://ghr.nlm.nih.gov/chromosome/13#resources]<br>Atlas Genetics Oncology (2012) 'chromosome 13' [http://atlasgeneticsoncology.org/Indexbychrom/idxa_13.html http://atlasgeneticsoncology.org/Indexbychrom/idxa_13.html]
=== References: ===
 
=== '''<references /><br>'''<br><br> ===

Revision as of 12:04, 29 November 2012

Chromosome 13 is one of 22 automsomal pairs of chromosomes found in humans. It is thought to contain about 114 million base pairs and codes for between 600 and 700 genes which code for various things from ATPase to specific diseases. It is widely associated breast cancer; gene BRCA2 and some bladder cancers as well as Wilson's disease which is a mutation of the ATP7B gene.  

There are also many chromosomal conditions associated with chromosome 13 including Patau syndrome which is trisomy of chromosome 13 and Retinoblastoma which can be caused by deletion of a specific region (13q14) containing the RB1 gene [1][2].

References:

  1. ↑ Genetics Home Reference (2012) 'chromosome 13' http://ghr.nlm.nih.gov/chromosome/13#resources
  2. ↑ Atlas Genetics Oncology (2012) 'chromosome 13' http://atlasgeneticsoncology.org/Indexbychrom/idxa_13.html



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