N-acetylglucosamine: Difference between revisions
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N-acetylglucosame is an [[Oligosaccharide|oligosaccharide]] added to the surface of red blood cells, and it is one of the oligosaccharides that specifies [[Blood group]]. It is added to the red blood cell surface by a [[Glycosyltransferase]] enzyme which is encoded for by a specific [[Allele]]. There are 3 different alleles that encode blood group I<sup>A </sup>, I<sup>B</sup> and I<sup>O</sup>. It is the I<sup>A</sup> allele that encodes for the specific glycosyltransferase enzyme which adds N-acetylglucosamine, and if the person has both alleles I<sup>A</sup>I<sup>A</sup> then they have A blood group. The I<sup>B </sup>allele codes for a different glycosyltransferase enzyme which adds a different [[Oligosaccharide]]<ref>Hartl Daniel L., Ruvolo Maryellen, (2012), Genetics, Analysis of genes and genomes, 8th edition, Canada, USA: Jones and Bartlet Publishers</ref>. | N-acetylglucosame is an [[Oligosaccharide|oligosaccharide]] added to the surface of red blood cells, and it is one of the oligosaccharides that specifies [[Blood group]]. It is added to the red blood cell surface by a [[Glycosyltransferase]] enzyme which is encoded for by a specific [[Allele]]. There are 3 different alleles that encode blood group I<sup>A </sup>, I<sup>B</sup> and I<sup>O</sup>. It is the I<sup>A</sup> allele that encodes for the specific glycosyltransferase enzyme which adds N-acetylglucosamine, and if the person has both alleles I<sup>A</sup>I<sup>A</sup> then they have A blood group. The I<sup>B </sup>allele codes for a different [[glycosyltransferase|glycosyltransferase]] enzyme which adds a different [[Oligosaccharide]]<ref>Hartl Daniel L., Ruvolo Maryellen, (2012), Genetics, Analysis of genes and genomes, 8th edition, Canada, USA: Jones and Bartlet Publishers</ref>. | ||
[[Image:Imgf000019 0001.png|348x250px|N-acetylglucosamine structure]]<br> | [[Image:Imgf000019 0001.png|348x250px|N-acetylglucosamine structure]]<br> | ||
=== References === | === References === | ||
<references /> | <references /><br> | ||
Picture: [http://www.google.com/patents/EP2007898A1 http://www.google.com/patents/EP2007898A1]<br> | |||
Picture: [http://www.google.com/patents/EP2007898A1 http://www.google.com/patents/EP2007898A1] | |||
<br> | |||
=== See also === | === See also === | ||
*[[Blood group systems]] | *[[Blood group systems]] | ||
Latest revision as of 02:10, 29 November 2013
N-acetylglucosame is an oligosaccharide added to the surface of red blood cells, and it is one of the oligosaccharides that specifies Blood group. It is added to the red blood cell surface by a Glycosyltransferase enzyme which is encoded for by a specific Allele. There are 3 different alleles that encode blood group IA , IB and IO. It is the IA allele that encodes for the specific glycosyltransferase enzyme which adds N-acetylglucosamine, and if the person has both alleles IAIA then they have A blood group. The IB allele codes for a different glycosyltransferase enzyme which adds a different Oligosaccharide[1].
References
- ↑ Hartl Daniel L., Ruvolo Maryellen, (2012), Genetics, Analysis of genes and genomes, 8th edition, Canada, USA: Jones and Bartlet Publishers
Picture: http://www.google.com/patents/EP2007898A1