Lipid droplets: Difference between revisions
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[[Lipid|Lipid]] droplets are lipid stores inside cells that are surrounded by a [[ | [[Lipid|Lipid]] droplets are lipid stores inside cells that are surrounded by a [[Phospholipid bilayer|phospholipid bilayer]] and are often found insidide adipocytes. Lipid droplets are able to store neutral lipids e.g. triaclycerides and [[Cholesterol|cholesterol]] esters that are synthesised in the [[Endoplasmic reticulum|endoplasmic reticulum]]. The lipids stored inside the droplets are neutral due to the fact they contain no [[Hydrophilic|hydrophilic]] head groups, instead all containing [[Hydrophobic|hydrophobic]] constituent molecules, that clump into droplets rather than bilayer (as would happen if they contained hydrophilic heads) <ref>This information was from: Alberts et al. (2008:625-626) Molecular Biology of the Cell, 5 edition, New York: Garland Science.</ref>. | ||
Formation | === Formation === | ||
Lipid droplets form when neutrally charged lipids become depositied betweent the layers within the endoplasmic reticulum membrane. Once deposited, the neutral lipids clump together to form a 3-D droplet, which buds off of the endoplasmic reticulum membrane and separates from the E.R. The lipid droplet is surrounded by a phospholipid bilayer that contains numerous proteins associated with lipid metabolism | Lipid droplets form when neutrally charged lipids become depositied betweent the layers within the endoplasmic reticulum membrane. Once deposited, the neutral lipids clump together to form a 3-D droplet, which buds off of the [[Endoplasmic_reticulum|endoplasmic reticulum]] (E.R.) membrane and separates from the E.R. The lipid droplet is surrounded by a phospholipid bilayer that contains numerous proteins associated with lipid metabolism <ref>This information is from: Alberts et al. (2008:625-626) Molecular Biology of the Cell, 5 edition, New York: Garland Science</ref>. | ||
=== '''References''' === | |||
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Latest revision as of 03:04, 29 November 2013
Lipid droplets are lipid stores inside cells that are surrounded by a phospholipid bilayer and are often found insidide adipocytes. Lipid droplets are able to store neutral lipids e.g. triaclycerides and cholesterol esters that are synthesised in the endoplasmic reticulum. The lipids stored inside the droplets are neutral due to the fact they contain no hydrophilic head groups, instead all containing hydrophobic constituent molecules, that clump into droplets rather than bilayer (as would happen if they contained hydrophilic heads) [1].
Formation
Lipid droplets form when neutrally charged lipids become depositied betweent the layers within the endoplasmic reticulum membrane. Once deposited, the neutral lipids clump together to form a 3-D droplet, which buds off of the endoplasmic reticulum (E.R.) membrane and separates from the E.R. The lipid droplet is surrounded by a phospholipid bilayer that contains numerous proteins associated with lipid metabolism [2].