Aspartic Acid: Difference between revisions

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Aspartic acid, also known as aspartate, is an [[Amino acid|amino acid]] with an acidic side chain. At normal [[PH|pH]] it usually carries a negative charge. This is due to a missing proton from the -COOH ([[Carboxylic acid|carboxylic acid]]) group.<br>It is coded for by the the three letter code Asp and the one letter code D&nbsp;<ref>Berg, Tymoczko and Stryer. (2006) Biochemistry, 6th edition, New York: WH Freeman</ref>.
<span style="font-family: Helvetica; font-size: 13pt; line-height: 1.5em; text-align: justify;">Aspartic
acid, also known as aspartate, is an </span>[https://teaching.ncl.ac.uk/bms/wiki/extensions/FCKeditor/fckeditor/editor/Amino%20acid <span style="color:#0013A9">amino acid</span>]<span style="font-family: Helvetica; font-size: 13pt; line-height: 1.5em; text-align: justify;"> with an acidic side chain. At
normal </span>[https://teaching.ncl.ac.uk/bms/wiki/extensions/FCKeditor/fckeditor/editor/PH <span style="color:#0013A9">pH</span>]<span style="font-family: Helvetica; font-size: 13pt; line-height: 1.5em; text-align: justify;"> it usually carries a negative charge. This
is due to a missing proton from the -COOH (</span>[https://teaching.ncl.ac.uk/bms/wiki/extensions/FCKeditor/fckeditor/editor/Carboxylic%20acid <span style="color:#0013A9">carboxylic acid</span>]<span style="font-family: Helvetica; font-size: 13pt; line-height: 1.5em; text-align: justify;">) group. Aspartic acid has the
chemical formula&nbsp;HOOCCH(NH</span><sub style="font-family: Helvetica; line-height: 1.5em; text-align: justify;">2</sub><span style="font-family: Helvetica; font-size: 13pt; line-height: 1.5em; text-align: justify;">)CH</span><sub style="font-family: Helvetica; line-height: 1.5em; text-align: justify;">2. </sub><span style="font-family: Helvetica; font-size: 13pt; line-height: 1.5em; text-align: justify;">Aspartic acid along
with glutamic acid is the only acidic amino acid with a pk</span><sub style="font-family: Helvetica; line-height: 1.5em; text-align: justify;">a</sub><span style="font-family: Helvetica; font-size: 13pt; line-height: 1.5em; text-align: justify;"> of 3.86.</span>
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<span lang="EN-US" style="font-size:13.0pt;font-family:Helvetica;mso-bidi-font-family:Helvetica">The
amino acid has both ‘L’ and ‘D’ isomers, and the&nbsp;</span><span lang="EN-US" style="font-size:11.0pt;font-family:Helvetica;mso-bidi-font-family:Helvetica">L</span><span lang="EN-US" style="font-size:13.0pt;font-family:Helvetica;mso-bidi-font-family:
Helvetica">-isomer of aspartate is one of the 22&nbsp;[http://en.wikipedia.org/wiki/Proteinogenic_amino_acid <span style="color:#0013A9">proteinogenic</span>]&nbsp;amino acids (those that are the building blocks of proteins). Most chemical syntheses will produce a ‘DL-aspartic acid’ which is a racemic mixture.</span><span lang="EN-US" style="font-size:11.0pt;
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=== Reference ===
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style='width:1pt;height:1pt;visibility:visible;mso-wrap-style:square'>
<v:imagedata src="file://localhost/Users/lucygee/Library/Caches/TemporaryItems/msoclip/0clip_image001.gif"
  o:title=""/>
</v:shape><![endif]--><!--[if !vml]-->[[Image:]]<!--[endif]--></span><span lang="EN-US" style="font-size:
13.0pt;font-family:Helvetica;mso-bidi-font-family:Helvetica">It is coded for by
the three letter code Asp and the one letter code D.<o:p></o:p></span>
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<references />academics.keene.edu/rblatchly/Chem220/hand/npaa/aawpka.htm&nbsp;<br>  
 
 


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Revision as of 16:37, 29 November 2013

Aspartic acid, also known as aspartate, is an amino acid with an acidic side chain. At normal pH it usually carries a negative charge. This is due to a missing proton from the -COOH (carboxylic acid) group. Aspartic acid has the chemical formula HOOCCH(NH2)CH2. Aspartic acid along with glutamic acid is the only acidic amino acid with a pka of 3.86. The amino acid has both ‘L’ and ‘D’ isomers, and the L-isomer of aspartate is one of the 22 proteinogenic amino acids (those that are the building blocks of proteins). Most chemical syntheses will produce a ‘DL-aspartic acid’ which is a racemic mixture.<o:p></o:p>

[[Image:]]It is coded for by the three letter code Asp and the one letter code D.<o:p></o:p>


academics.keene.edu/rblatchly/Chem220/hand/npaa/aawpka.htm 



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