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| [[DNA|DNA]] topoisomerase plays an impotant role in breaking the [[Phosphodiester_bond|phosphodiester bond]] by binding covalently onto the DNA backbone [[Phosphate|phosphate]]. It acst as a [[reversible nuclease|reversible nuclease]]. This whole process is a reversible one, whereby before the [[Proteins|protein]] leaves, the phosophodiester bonds are re-made. There are two types of DNA topoisomerase, [[DNA topoisomerase I|topoisomerase I]] and [[DNA topoisomerase II|topoismerase II]]<ref>Alberts, BA, 2008. Molecular Biology of The Cell. 5th ed. New York: Garland Science.</ref>.<br> | | See [[DNA_topoisomerase|DNA topoisomerase ]] |
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| === '''Reference:''' ===
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Latest revision as of 07:03, 12 October 2014