B cells: Difference between revisions
Jump to navigation
Jump to search
Created page with " B cells or B lymphocytes develop from hematopoietic stem cells in the bone marrow and are involved in the humoral response. The receptor of the B cell binds antigen and del..." |
No edit summary |
||
| Line 1: | Line 1: | ||
B cells or B lymphocytes develop from hematopoietic stem cells in the bone marrow and are involved in the humoral response. The receptor of the B cell binds antigen and delivers this inside the cell in a vesicle where the antigen undergoes processing and is then presented on the cell surface as a complex with an MHC class 2 molecule. CD4+ T cells then respond to this antigen presentation by releasing cytokines leading to B cell proliferation and differentiation. B cells differentiate into plasma memory cells and antibody secreting cells. | B cells or B lymphocytes develop from hematopoietic stem cells in the bone marrow and are involved in the humoral response. The receptor of the B cell binds an antigen and delivers this inside the cell in a vesicle where the antigen undergoes processing and is then presented on the cell surface as a complex with an MHC class 2 molecule. CD4+ T cells then respond to this antigen presentation by releasing cytokines leading to B cell proliferation and differentiation. B cells differentiate into plasma memory cells and antibody secreting cells. | ||
<br> | |||
Reference: | |||
Reference: | |||
Murphy, K. (2012) Janeway's Immunobiology. 8th Edition. New York: Garland Sciences. Chapter 8.1 and Chapter 10 introduction. | Murphy, K. (2012) Janeway's Immunobiology. 8th Edition. New York: Garland Sciences. Chapter 8.1 and Chapter 10 introduction. | ||
Revision as of 11:49, 16 October 2014
B cells or B lymphocytes develop from hematopoietic stem cells in the bone marrow and are involved in the humoral response. The receptor of the B cell binds an antigen and delivers this inside the cell in a vesicle where the antigen undergoes processing and is then presented on the cell surface as a complex with an MHC class 2 molecule. CD4+ T cells then respond to this antigen presentation by releasing cytokines leading to B cell proliferation and differentiation. B cells differentiate into plasma memory cells and antibody secreting cells.
Reference:
Murphy, K. (2012) Janeway's Immunobiology. 8th Edition. New York: Garland Sciences. Chapter 8.1 and Chapter 10 introduction.