Cyclic AMP: Difference between revisions
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Cyclic AMP (cAMP) is a [[Second messengers|second messenger]] used in cell signalling. It is synthesised from [[ATP|ATP]] by the [[Enzyme|enzyme]] [[Adenylyl cyclase|adenylyl cyclase]]. | Cyclic AMP (cAMP) is a [[Second messengers|second messenger]] used in cell signalling. It is synthesised from [[ATP|ATP]] by the [[Enzyme|enzyme]] [[Adenylyl cyclase|adenylyl cyclase]]. | ||
Production of cyclic AMP results in the activation of [[Protein kinase A|Protein kinase A]], which triggers cellular responses by activating [[Enzymes|enzymes]], stimulating cellular secretion or opening ion channels<ref>Alberts et al. (2008). "Molecular Biology of the Cell" (5th edition); page 906</ref>. | The concentration within a cell of cyclic AMP is normally around 10<sup>-7 </sup>however an extracellular signal can raise those levels within the cell by a factor of 20 within seconds.<ref>Alberts et al. (2008). "Molecular Biology of the Cell" (5th edition); page 854</ref> <sup></sup>Production of cyclic AMP results in the activation of [[Protein kinase A|Protein kinase A]], which triggers cellular responses by activating [[Enzymes|enzymes]], stimulating cellular secretion or opening ion channels<ref>Alberts et al. (2008). "Molecular Biology of the Cell" (5th edition); page 906</ref>. | ||
=== References === | === References === | ||
<references /> | <references /> | ||
Revision as of 12:16, 20 October 2014
Cyclic AMP (cAMP) is a second messenger used in cell signalling. It is synthesised from ATP by the enzyme adenylyl cyclase.
The concentration within a cell of cyclic AMP is normally around 10-7 however an extracellular signal can raise those levels within the cell by a factor of 20 within seconds.[1] Production of cyclic AMP results in the activation of Protein kinase A, which triggers cellular responses by activating enzymes, stimulating cellular secretion or opening ion channels[2].