Allosteric control: Difference between revisions
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Created page with "Allosteric control or regulation, is when a molecule effects the action of an enzyme, by binding, but NOT to the active site, they bind to a specific allosteric site. On binding,..." |
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Allosteric control or regulation, is when a molecule effects the action of an enzyme, by binding, but NOT to the active site, they bind to a specific allosteric site. On binding, they typically switch on/increase protein activity, or switch off/decrease protein activity. They cause these changes in levels of activity in the enzyme by causing a conformational change in the protein, leading to an alteration in the enzyme's active site, which therefore effects catalytic activity. They form part of a complex system of negative feedback and feedback loops. | <p>Allosteric control or regulation, is when a molecule effects the action of an enzyme, by binding, but NOT to the active site, they bind to a specific allosteric site. On binding, they typically switch on/increase protein activity, or switch off/decrease protein activity. They cause these changes in levels of activity in the enzyme by causing a conformational change in the protein, leading to an alteration in the enzyme's active site, which therefore effects catalytic activity. They form part of a complex system of negative feedback and feedback loops. | ||
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<h2> References </h2> | |||
<p>http://www.biology.arizona.edu/biochemistry/problem_sets/energy_enzymes_catalysis/03t.html | |||
</p> |
Revision as of 03:54, 23 October 2014
Allosteric control or regulation, is when a molecule effects the action of an enzyme, by binding, but NOT to the active site, they bind to a specific allosteric site. On binding, they typically switch on/increase protein activity, or switch off/decrease protein activity. They cause these changes in levels of activity in the enzyme by causing a conformational change in the protein, leading to an alteration in the enzyme's active site, which therefore effects catalytic activity. They form part of a complex system of negative feedback and feedback loops.
References
http://www.biology.arizona.edu/biochemistry/problem_sets/energy_enzymes_catalysis/03t.html