G-protein linked receptor: Difference between revisions

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Created page with " G-protein linked receptors, also known as G-protein Coupled receptors, are a family of receptor signal transducers which are involved in signalling pathways within cells.<r..."
 
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Cleaned up the entry. Added in some links. Sorted out the references. Poorly formated. Didn't follow publication guidelines.
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&nbsp;G-protein linked receptors, also known as G-protein Coupled receptors, are a family of receptor signal transducers which are involved in signalling pathways within cells.<ref>Cascieri.Fong.Graziano.Tota.Candelore.Strader. (1996) ‘Signaling through G-Protein-coupled Receptors’, pg93, in Heldin,C. Purton,M and International Union of Biochemistry and Molecular Biology. (ed) Signal Transduction, London: Chapman &amp;amp; Hall in association with the IUBMB</ref> Subtypes, each with an endogenous agonist, are involved in maintaining physiological systems such as rhodopsin in rod cells required for vision.<ref>Cascieri.Fong.Graziano.Tota.Candelore.Strader. (1996) ‘Signaling through G-Protein-coupled Receptors’, pg94, in Heldin,C. Purton,M and International Union of Biochemistry and Molecular Biology. (ed) Signal Transduction, London: Chapman &amp;amp; Hall in association with the IUBMB</ref>  
G-protein linked receptors, also known as [[G-protein_Coupled_Receptor|G-protein Coupled receptors]], are a family of receptor signal transducers which are involved in signalling pathways within cells&nbsp;<ref>Cascieri.Fong.Graziano.Tota.Candelore.Strader. (1996) ‘Signaling through G-Protein-coupled Receptors’, pg93, in Heldin,C. Purton,M and International Union of Biochemistry and Molecular Biology. (ed) Signal Transduction, London: Chapman &amp;amp;amp; Hall in association with the IUBMB</ref>.&nbsp;Subtypes, each with an endogenous [[agonist|agonist]], are involved in maintaining physiological systems such as [[rhodopsin|rhodopsin]] in [[rod cells|rod cells]] required for vision&nbsp;<ref>Cascieri.Fong.Graziano.Tota.Candelore.Strader. (1996) ‘Signaling through G-Protein-coupled Receptors’, pg94, in Heldin,C. Purton,M and International Union of Biochemistry and Molecular Biology. (ed) Signal Transduction, London: Chapman &amp;amp;amp; Hall in association with the IUBMB</ref>.<br>  


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=== Structure  ===


= Structure  =
The structure of these proteins comprises of seven [[transmembrane helices|transmembrane helices]] with an extracellular ligand binding domain and an intracellular G-protein binding domain&nbsp;<ref>Cascieri.Fong.Graziano.Tota.Candelore.Strader. (1996) ‘Signaling through G-Protein-coupled Receptors’, pg94, in Heldin,C. Purton,M and International Union of Biochemistry and Molecular Biology. (ed) Signal Transduction, London: Chapman &amp;amp;amp; Hall in association with the IUBMB</ref>.<br>


The structure of these proteins comprises of seven transmembrane helices with an extracellular ligand binding domain and an intracellular G-protein binding domain.<ref>Cascieri.Fong.Graziano.Tota.Candelore.Strader. (1996) ‘Signaling through G-Protein-coupled Receptors’, pg94, in Heldin,C. Purton,M and International Union of Biochemistry and Molecular Biology. (ed) Signal Transduction, London: Chapman &amp;amp; Hall in association with the IUBMB</ref>
=== References  ===
 
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= References  =


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Revision as of 01:32, 24 October 2014

G-protein linked receptors, also known as G-protein Coupled receptors, are a family of receptor signal transducers which are involved in signalling pathways within cells [1]. Subtypes, each with an endogenous agonist, are involved in maintaining physiological systems such as rhodopsin in rod cells required for vision [2].

Structure

The structure of these proteins comprises of seven transmembrane helices with an extracellular ligand binding domain and an intracellular G-protein binding domain [3].

References

  1. Cascieri.Fong.Graziano.Tota.Candelore.Strader. (1996) ‘Signaling through G-Protein-coupled Receptors’, pg93, in Heldin,C. Purton,M and International Union of Biochemistry and Molecular Biology. (ed) Signal Transduction, London: Chapman &amp;amp; Hall in association with the IUBMB
  2. Cascieri.Fong.Graziano.Tota.Candelore.Strader. (1996) ‘Signaling through G-Protein-coupled Receptors’, pg94, in Heldin,C. Purton,M and International Union of Biochemistry and Molecular Biology. (ed) Signal Transduction, London: Chapman &amp;amp; Hall in association with the IUBMB
  3. Cascieri.Fong.Graziano.Tota.Candelore.Strader. (1996) ‘Signaling through G-Protein-coupled Receptors’, pg94, in Heldin,C. Purton,M and International Union of Biochemistry and Molecular Biology. (ed) Signal Transduction, London: Chapman &amp;amp; Hall in association with the IUBMB