ANTI-INFLAMMATORY DRUGS: Difference between revisions
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There are two groups of anti-inflammatory drugs | There are two groups of anti-inflammatory drugs: | ||
< | #[[Non-steroidal anti-inflammatory drugs|Non-steroidal anti-inflammatory drugs]] | ||
#[[Steroidal anti-inflammatory drugs|Steroidal anti-inflammatory drugs]]. | |||
Non-steroidal anti-inflammatory drugs, also referred to as NSAID's often act on [[COX-2 enzymes|COX-2 enzymes]] which are mainly in the human [[Central_nervous_system|central nervous system]] in order to treat pain; this is the mechanism of action for paracetamol<ref>Hinz,B. Cheremina, O. Brune, K. (2008) 'Do selective cyclo-oxygenase-2 inhibitors and traditional non-steroidal anti-inflammatory drugs increase the risk of atherothrombosis? Meta-analysis of randomised trials', The Journal of the Federation of American Societies for Experimental Biology, vol. 22, no. 2, February, pp. 383-390. doi:10.1096/fj.07-8506com.</ref>. NSAID's also inhibit the activity of COX-1 ([[cyclooxygenase-1|cyclooxygenase-1]]) enzymes. | |||
=== References === | |||
<references /> | <references /> | ||
Revision as of 04:25, 24 October 2014
There are two groups of anti-inflammatory drugs:
Non-steroidal anti-inflammatory drugs, also referred to as NSAID's often act on COX-2 enzymes which are mainly in the human central nervous system in order to treat pain; this is the mechanism of action for paracetamol[1]. NSAID's also inhibit the activity of COX-1 (cyclooxygenase-1) enzymes.
References
- ↑ Hinz,B. Cheremina, O. Brune, K. (2008) 'Do selective cyclo-oxygenase-2 inhibitors and traditional non-steroidal anti-inflammatory drugs increase the risk of atherothrombosis? Meta-analysis of randomised trials', The Journal of the Federation of American Societies for Experimental Biology, vol. 22, no. 2, February, pp. 383-390. doi:10.1096/fj.07-8506com.