Trastuzumab: Difference between revisions

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&nbsp;Trastuzumab, known more commonly as Herceptin, is a medicine used to treat some [[Breast Cancer|breast]] and stomach [[Cancer|cancers]]. The human epidermal growth factor receptor 2 is a [[Protein|protein]] present in ordinary human cells. The levels of this protein are abnormally high in [[Cancer|cancer]] patients; therefore they are known as HEF2 positive.&nbsp;<ref>NHS choices,2014,Herceptin.[online]Available at:http://www.nhs.uk/conditions/herceptin/Pages/Introduction.aspx[Accessed 25 November 2014]</ref>&nbsp;Herceptin attaches itself to the HER2 receptors on the surface of cancer cells; therefore blocking these [[Cell|cells]] from any growth signals they may have otherwise received. After this attachment, herceptin causes the [[Immune system|immune system]] to kill the cancer cells that it is attached to.&nbsp;<ref>Breast Cancer Care,2014,Herceptin[online]Available at:https://www.breastcancercare.org.uk/breast-cancer-information/treating-breast-cancer/targeted-therapy/trastuzumab-herceptin[Accessed 25 November 2014]</ref>  
Trastuzumab, known more commonly as [[Herceptin|Herceptin]], is a medicine used to treat some [[Breast Cancer|breast]] and stomach [[Cancer|cancers]]. The human epidermal growth factor receptor 2 is a [[Protein|protein]] present in ordinary human cells. The levels of this protein are abnormally high in [[Cancer|cancer]] patients; therefore they are known as HEF2 positive.&nbsp;<ref>NHS choices,2014,Herceptin.[online]Available at:http://www.nhs.uk/conditions/herceptin/Pages/Introduction.aspx[Accessed 25 November 2014]</ref>&nbsp;Herceptin attaches itself to the HER2 receptors on the surface of cancer cells; therefore blocking these [[Cell|cells]] from any growth signals they may have otherwise received. After this attachment, herceptin causes the [[Immune system|immune system]] to kill the cancer cells that it is attached to&nbsp;<ref>Breast Cancer Care,2014,Herceptin[online]Available at:https://www.breastcancercare.org.uk/breast-cancer-information/treating-breast-cancer/targeted-therapy/trastuzumab-herceptin[Accessed 25 November 2014]</ref>.<br>  


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Revision as of 12:49, 25 November 2014

Trastuzumab, known more commonly as Herceptin, is a medicine used to treat some breast and stomach cancers. The human epidermal growth factor receptor 2 is a protein present in ordinary human cells. The levels of this protein are abnormally high in cancer patients; therefore they are known as HEF2 positive. [1] Herceptin attaches itself to the HER2 receptors on the surface of cancer cells; therefore blocking these cells from any growth signals they may have otherwise received. After this attachment, herceptin causes the immune system to kill the cancer cells that it is attached to [2].

References

  1. NHS choices,2014,Herceptin.[online]Available at:http://www.nhs.uk/conditions/herceptin/Pages/Introduction.aspx[Accessed 25 November 2014]
  2. Breast Cancer Care,2014,Herceptin[online]Available at:https://www.breastcancercare.org.uk/breast-cancer-information/treating-breast-cancer/targeted-therapy/trastuzumab-herceptin[Accessed 25 November 2014]