Penetrance: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
Penetrance is the percentage of the expression of the [[Phenotype|phenotype]] in an [[Organism|organism]] from its adjacent [[Genotype|genotype]] <ref>Hartl, D.L., Ruvolo, M. (2012) Genetics:Analysis Of Genes And Genomes, United States of America: Jones and Bartlett</ref>, ie. how many members of a [[population|population]] with a specific genotype that show the expected phenotype. | |||
An example of complete pentrance is neurofibromatosis type 1. The symptoms of this mutation will be shown in all of the mutants - 100% penetrance. <ref>NHS. (ND). Penetrance. Available at: http://www.geneticseducation.nhs.uk/genetic-glossary/221-penetrance (Accessed at: 26/11/14)</ref> | An example of complete pentrance is neurofibromatosis type 1. The symptoms of this mutation will be shown in all of the mutants - 100% penetrance. <ref>NHS. (ND). Penetrance. Available at: http://www.geneticseducation.nhs.uk/genetic-glossary/221-penetrance (Accessed at: 26/11/14)</ref> | ||
Incomplete penetrance is when some individuals with a particular (dominant) mutation express a wild type phenotype.An example is polydactyly. | Incomplete penetrance is when some individuals with a particular (dominant) mutation express a wild type phenotype.An example is polydactyly. | ||
=== Reference === | |||
<references /> | <references /> | ||
Revision as of 23:19, 26 November 2014
Penetrance is the percentage of the expression of the phenotype in an organism from its adjacent genotype [1], ie. how many members of a population with a specific genotype that show the expected phenotype.
An example of complete pentrance is neurofibromatosis type 1. The symptoms of this mutation will be shown in all of the mutants - 100% penetrance. [2]
Incomplete penetrance is when some individuals with a particular (dominant) mutation express a wild type phenotype.An example is polydactyly.
Reference
- ↑ Hartl, D.L., Ruvolo, M. (2012) Genetics:Analysis Of Genes And Genomes, United States of America: Jones and Bartlett
- ↑ NHS. (ND). Penetrance. Available at: http://www.geneticseducation.nhs.uk/genetic-glossary/221-penetrance (Accessed at: 26/11/14)