Pre-Initiation Complex: Difference between revisions
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The Pre-Initiation Complex (PIC) is an assembly of General Transcription Factors (GTF's) onto the Core (Basal) region of DNA. These GTF's all have specific roles and together they initiate transcription. Together the GTF's form the PIC complex in the following order: TFIID, TFIIA, TFIIB (this brings in RNA Polymerase II), TFIIF, TFIIE & TFIIH. | The Pre-Initiation Complex (PIC) is an assembly of General Transcription Factors (GTF's) onto the Core (Basal) region of DNA. These GTF's all have specific roles and together they initiate transcription. Together the GTF's form the PIC complex in the following order: TFIID, TFIIA, TFIIB (this brings in RNA Polymerase II), TFIIF, TFIIE & TFIIH. | ||
Latest revision as of 14:09, 20 October 2015
The Pre-Initiation Complex (PIC) is an assembly of General Transcription Factors (GTF's) onto the Core (Basal) region of DNA. These GTF's all have specific roles and together they initiate transcription. Together the GTF's form the PIC complex in the following order: TFIID, TFIIA, TFIIB (this brings in RNA Polymerase II), TFIIF, TFIIE & TFIIH.