Presynaptic and postsynaptic neurons: Difference between revisions

From The School of Biomedical Sciences Wiki
Jump to navigation Jump to search
Nnjm2 (talk | contribs)
No edit summary
Nnjm2 (talk | contribs)
No edit summary
Line 1: Line 1:
=== Presynaptic neuron  ===
=== Presynaptic neuron  ===


A presynaptic neuron is a[[Neuron|neuron (nerve]] cell) that fires the [[Neurotransmitter|neurotransmitter]] as a result of an [[Action potential|action potential]] entering its axon terminal.
A presynaptic neuron is a[[Neuron|neuron (nerve]] cell) that fires the [[Neurotransmitter|neurotransmitter]] as a result of an [[Action potential|action potential]] entering its axon terminal.  


In both the central and peripheral nervous systems in mammals, presynaptic terminals mostly operate in the same way. Vesicles in the synapse form a ‘synaptic pool’ when they are ready for exocytosis-meaning they are readily releasable. When an action potential arrives at the nerve terminal the electrical signal induces opening of voltage gated Ca<sup>2+</sup> channels. <br>  
In both the central and peripheral nervous systems in mammals, presynaptic terminals mostly operate in the same way. Vesicles in the synapse form a ‘synaptic pool’ when they are ready for exocytosis-meaning they are readily releasable. When an action potential arrives at the nerve terminal the electrical signal induces opening of voltage gated Ca<sup>2+</sup> channels. <br>  
Line 7: Line 7:
=== Postsynaptic neuron  ===
=== Postsynaptic neuron  ===


A postsynaptic neuron in a [[Neuron|neuron]] (nerve cell) that receives the [[Neurotransmitter|neurotransmitter]] after it has crossed the [[Synapse|synapse]] and may experience an [[Action potential|action potential]] if the [[Neurotransmitter|neurotransmitter is]] strong enough.
A postsynaptic neuron in a [[Neuron|neuron]] (nerve cell) that receives the [[Neurotransmitter|neurotransmitter]] after it has crossed the [[Synapse|synapse]] and may experience an [[Action potential|action potential]] if the [[Neurotransmitter|neurotransmitter is]] strong enough.  


Postsynaptic neurons work through [[Summation|temporal summation and]] [[Summation|spatial summation]].  
Postsynaptic neurons work through [[Summation|temporal summation and]] [[Summation|spatial summation]].  


Through neurotransmission there can also be [[Divergence|divergence]] or [[Convergence|convergence<ref>Sumiko Mochida (2015 Presynaptic Terminals, Tokyo Japan : Springer</ref><ref>Alberts B, Johnson A, Lewis J, Raff M, Roberts K, Walkter P (2008) Molecular Biology Of The Cell, 5th edition, New York: Garland Science. 676, 683.</ref>]].<br>  
Through neurotransmission there can also be [[Divergence|divergence]] or [[Convergence|convergence]]<ref>Sumiko Mochida (2015 Presynaptic Terminals, Tokyo Japan : Springer</ref><ref>Alberts B, Johnson A, Lewis J, Raff M, Roberts K, Walkter P (2008) Molecular Biology Of The Cell, 5th edition, New York: Garland Science. 676, 683.</ref>


=== References ===
=== References ===


<references />  
<references />  


<br>
<br>  


<br>
<br>

Revision as of 19:55, 20 October 2015

Presynaptic neuron

A presynaptic neuron is aneuron (nerve cell) that fires the neurotransmitter as a result of an action potential entering its axon terminal.

In both the central and peripheral nervous systems in mammals, presynaptic terminals mostly operate in the same way. Vesicles in the synapse form a ‘synaptic pool’ when they are ready for exocytosis-meaning they are readily releasable. When an action potential arrives at the nerve terminal the electrical signal induces opening of voltage gated Ca2+ channels.

Postsynaptic neuron

A postsynaptic neuron in a neuron (nerve cell) that receives the neurotransmitter after it has crossed the synapse and may experience an action potential if the neurotransmitter is strong enough.

Postsynaptic neurons work through temporal summation and spatial summation.

Through neurotransmission there can also be divergence or convergence[1][2]

References

  1. Sumiko Mochida (2015 Presynaptic Terminals, Tokyo Japan : Springer
  2. Alberts B, Johnson A, Lewis J, Raff M, Roberts K, Walkter P (2008) Molecular Biology Of The Cell, 5th edition, New York: Garland Science. 676, 683.