Resting membrane potential: Difference between revisions

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The resting membrane potential is when the net flow of [[Ions|ions]] across the [[Plasma membrane|plasma membrane]] is zero. In humans this is said to be around -70mV<ref>Alberts B, Johnson A, Lewis J, Raff M, Roberts K, Walter P. (2008) Molecular Biology of the Cell, 5th edition, New York: Garland Science (page 669)</ref>.&nbsp; Even resting potentials are very active as sodium and potassium ions are constantly being actively transported by the [[Sodium potassium pump|sodium-potassium pump]], but some [[potassium|potassium]] [[ions|ions]] leak back through the potassium ion leak channel.  
The resting membrane potential of a neurone is when the net flow of [[Ions|ions]] across the [[Plasma membrane|plasma membrane]] equals zero. In humans this is said to be around -70mV<ref>Alberts B, Johnson A, Lewis J, Raff M, Roberts K, Walter P. (2008) Molecular Biology of the Cell, 5th edition, New York: Garland Science (page 669)</ref>.&nbsp; This means that the inside of the cell is negatively charged in comparison to the outside. Resting membrane potentials are maintained by two different types of ion channels- the [sodium-potassium pump] and the [sodium and potassium leak channels]. The sodium-potassium pump moves three sodium ions out of the cell for every two potassium ions it moves into the cell. Therefore more positively charged ions are being removed from the cell than are entering it making the inside environment of the cell comparatively negative to the outside.  


=== References  ===
=== References  ===


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Revision as of 13:54, 23 October 2015

The resting membrane potential of a neurone is when the net flow of ions across the plasma membrane equals zero. In humans this is said to be around -70mV[1].  This means that the inside of the cell is negatively charged in comparison to the outside. Resting membrane potentials are maintained by two different types of ion channels- the [sodium-potassium pump] and the [sodium and potassium leak channels]. The sodium-potassium pump moves three sodium ions out of the cell for every two potassium ions it moves into the cell. Therefore more positively charged ions are being removed from the cell than are entering it making the inside environment of the cell comparatively negative to the outside.

References

  1. Alberts B, Johnson A, Lewis J, Raff M, Roberts K, Walter P. (2008) Molecular Biology of the Cell, 5th edition, New York: Garland Science (page 669)