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= Micro RNA (miRNA) = | = Micro RNA (miRNA) = | ||
Micro RNA (miRNA) is one class of low molecular weight [[RNA|RNA]](about 21 nucleotides long) which is found in [[Eukaryotic cells|eukaryotic cells]]. Like [[MRNA|mRNA]], miRNA is synthesised by [[RNA polymerase II|RNA polymerase II]] but it's non-[[Protein|protein]] encoding RNA <ref>Alberts B, Johnson A, Lewis J, Raff M, Roberts K, Walter P,2008, Molecular Biology of the Cell,5th Edition, New York, Garland Science pg 493-4</ref>. Micro RNA molecules are complementary to mRNA molecules. They can bind to mRNA molecules and inhibit their translation resulting in a loss of gene expression<ref>Jeremy M. Berg, Biochemistry 7th edition, chapter 4 page 128</ref>.<br> | Micro RNA (miRNA) is one class of low molecular weight [[RNA|RNA]](about 21 nucleotides long) which is found in [[Eukaryotic cells|eukaryotic cells]]. Like [[MRNA|mRNA]], miRNA is synthesised by [[RNA polymerase II|RNA polymerase II]] but it's non-[[Protein|protein]] encoding RNA <ref>Alberts B, Johnson A, Lewis J, Raff M, Roberts K, Walter P,2008, Molecular Biology of the Cell,5th Edition, New York, Garland Science pg 493-4</ref>. Micro RNA molecules are complementary to mRNA molecules. They can bind to mRNA molecules and inhibit their translation resulting in a loss of gene expression<ref>Jeremy M. Berg, John L. Tymoczko, Lubert Stryer Biochemistry 7th edition, chapter 4 page 128</ref>.<br> | ||
=== References === | === References === | ||
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Latest revision as of 18:48, 21 November 2015
Micro RNA (miRNA)
Micro RNA (miRNA) is one class of low molecular weight RNA(about 21 nucleotides long) which is found in eukaryotic cells. Like mRNA, miRNA is synthesised by RNA polymerase II but it's non-protein encoding RNA [1]. Micro RNA molecules are complementary to mRNA molecules. They can bind to mRNA molecules and inhibit their translation resulting in a loss of gene expression[2].