Guanine nucleotide exchange factor: Difference between revisions
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Guanine nucleotide exchange factors (GEF) activate small [[GTPase|GTPases]] such as [[Ras|Ras]] by mediating the dissociation of GDP allowing GTP to bind | Guanine nucleotide exchange factors (GEF) activate small [[GTPase|GTPases]] such as [[Ras|Ras]] by mediating the dissociation of [[GDP|GDP]] allowing [[GTP|GTP]] to bind <ref>Alberts R, Johnson A, Lewis J, Morgan D, Raff M, Roberts K, Walter P. (2015) Molecular biology of the cell. 6th ed. New York: Garland Science. (p. 157)</ref>.<br> | ||
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