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Spectrin is a [[ | Spectrin is a filamentous [[Protein|protein]] that is associated with the cytosolic side of the [[Plasma membrane|plasma membrane]] in red [[Red blood cells|blood cells]], forming a network that supports the membrane. This is particularly important in red blood cells so that they maintain their concave structure and so can continue to carry [[Oxygen|oxygen]] around the blood stream. Spectrin helps red blood cell to withstand high presure which exerted on its membrance when travelling in narrow capilaries<ref>Alberts B. Molecular biology of the cell. New York: Garland Science; 2008.</ref>. Spectrin is also present in muscle fibres and is found as a tetramer of two alpha and two beta subunits in [[Actin|actin]] filaments<ref>Alberts, Johnson, Lewis, Raff, Roberts, Walter, 2008 :1007</ref>. | ||
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Latest revision as of 03:33, 28 November 2015
Spectrin is a filamentous protein that is associated with the cytosolic side of the plasma membrane in red blood cells, forming a network that supports the membrane. This is particularly important in red blood cells so that they maintain their concave structure and so can continue to carry oxygen around the blood stream. Spectrin helps red blood cell to withstand high presure which exerted on its membrance when travelling in narrow capilaries[1]. Spectrin is also present in muscle fibres and is found as a tetramer of two alpha and two beta subunits in actin filaments[2].
References