Sodium-calcium Exchanger: Difference between revisions
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The sodium-calcium exchanger is an [[Antiporter|antiporter]] in the[[ | The sodium-calcium exchanger is an [[Antiporter|antiporter]] in the [[Plasma membrane|plasma membrane]] of a cell that transports sodium ions into the cell and calcium ions out of the cell by [[Secondary active transport|secondary active transport]]. It uses the downward Na<sup>+</sup> gradient into the cell created by [[Sodium potassium pump|sodium pumps]] using ATP to power the uphill transport of Ca<sup>2+</sup> out of the cell. It is effective at high Ca<sup>2+</sup><sup></sup><sup></sup> concentrations. | ||
The sodium-calcium exchanger is important in the regulation of calcium ions in a cell. Cytosolic calcium concentration is kept low because calcium ions can act as a trigger for many processes, such as [[ | The sodium-calcium exchanger is important in the regulation of calcium ions in a cell. Cytosolic calcium concentration is kept low because calcium ions can act as a trigger for many processes, such as [[Muscle contraction|muscle contraction]] and [[Cell signalling pathways|cell signalling pathways]]. |
Latest revision as of 15:41, 3 December 2015
The sodium-calcium exchanger is an antiporter in the plasma membrane of a cell that transports sodium ions into the cell and calcium ions out of the cell by secondary active transport. It uses the downward Na+ gradient into the cell created by sodium pumps using ATP to power the uphill transport of Ca2+ out of the cell. It is effective at high Ca2+ concentrations.
The sodium-calcium exchanger is important in the regulation of calcium ions in a cell. Cytosolic calcium concentration is kept low because calcium ions can act as a trigger for many processes, such as muscle contraction and cell signalling pathways.