Depolarisation: Difference between revisions

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When something is polarised its ends are oppositely charged. So, depolarisation is when the difference is balanced, the ends no longer have different charges.  
When something is polarised its ends are oppositely charged. So, depolarisation is when the difference is balanced, the ends no longer have different charges.  


A depolarised neuron is when the cells membrane potentail becomes more postive. This occurs when the cell is stimulated; the membrane becomes more permeable to sodium gated ion channels allowing them to move into the cell, making it less negative&nbsp;<ref>West One. A depolarised neuron (a stimulated neuron). [ONLINE] Available at: http://tle.westone.wa.gov.au/content/file/969144ed-0d3b-fa04-2e88-8b23de2a630c/1/human_bio_science_3b.zip/content/002_nervous_control/page_11.htm. [Accessed 23 November 14].</ref>.
For example in neural stimulation,&nbsp;a&nbsp;neurone can&nbsp;become depolarised&nbsp;when the cells resting membrane potential (-65mV) becomes more positive relative to the outside of the cell (+40mV). This occurs when the cell is stimulated via an action potential; the membrane&nbsp;contains voltage-gated sodium channels that become more permeable to sodium ions allowing them to&nbsp;diffuse&nbsp;out of&nbsp;the cell down their concentration gradient, making the overall charge more negative relative to the outside.<br>
 
An example of depolarisation is when the [[Sodium voltage-gated ion channels|sodium voltage-gated ion channels]] open in the neuronal membrane to undo the polarisation of the [[Resting membrane potential|resting membrane potential]].<br>  


=== References  ===
=== References  ===


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Revision as of 13:59, 20 October 2016

When something is polarised its ends are oppositely charged. So, depolarisation is when the difference is balanced, the ends no longer have different charges.

For example in neural stimulation, a neurone can become depolarised when the cells resting membrane potential (-65mV) becomes more positive relative to the outside of the cell (+40mV). This occurs when the cell is stimulated via an action potential; the membrane contains voltage-gated sodium channels that become more permeable to sodium ions allowing them to diffuse out of the cell down their concentration gradient, making the overall charge more negative relative to the outside.

References