Α-Ketoglutarate dehydrogenase: Difference between revisions
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Pronounced alpha-ketoglutarate dehydrogenase this is a complex formed from three kinds of enzymes found in the citric acid cycle (CAC).<br>It catalyses the oxidative decarboxylation of alpha-ketoglutarate to succinyl | Pronounced alpha-ketoglutarate dehydrogenase this is a complex formed from three kinds of enzymes found in the citric acid cycle (CAC).<br>It catalyses the oxidative decarboxylation of alpha-ketoglutarate to succinyl CoA [1]. | ||
The reaction is as follows:<br>alpha-Ketoglutarate + NAD + CoA -----► Succinyl CoA + CO2 + NADH <sup></sup> | The reaction is as follows:<br>alpha-Ketoglutarate + NAD + CoA -----► Succinyl CoA + CO2 + NADH <sup></sup> | ||
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1. Berg J, Tymoczko J, Gatto G, Stryer L. Biochemistry. 8th ed. New York: W.H. Freeman; 2015. p. 505<br> | 1. Berg J, Tymoczko J, Gatto G, Stryer L. Biochemistry. 8th ed. New York: W.H. Freeman; 2015. p. 505<br> | ||
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To be completed | To be completed | ||
Revision as of 22:33, 30 November 2016
Pronounced alpha-ketoglutarate dehydrogenase this is a complex formed from three kinds of enzymes found in the citric acid cycle (CAC).
It catalyses the oxidative decarboxylation of alpha-ketoglutarate to succinyl CoA [1].
The reaction is as follows:
alpha-Ketoglutarate + NAD + CoA -----► Succinyl CoA + CO2 + NADH
1. Berg J, Tymoczko J, Gatto G, Stryer L. Biochemistry. 8th ed. New York: W.H. Freeman; 2015. p. 505
To be completed