Mismatch Repair: Difference between revisions

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 Mismatch repair is the process that occurs in order to repair DNA. Where there are mismatched bases within the DNA molecule, an enzyme will reorganise them.
 Mismatch repair is the process that occurs in order to repair DNA. Where there are mismatched bases within the DNA molecule, an enzyme will reorganise them.  


This is done by cutting out the segment of incorrect base pairs of just one strand of the DNA molecule. The remaining strand then acts as a template in which the complimentary strand is synthesised. This process ultimately results in what is called gene conversion<ref>Hartl D. L., Ruvolo M. (2012) Genetics, Analysis of Genes and Genomes, Eighth Edition, Burlington, Jones &amp; Bartlett Learning</ref>.
This is done by cutting out the segment of incorrect base pairs of just one strand of the DNA molecule. The remaining strand then acts as a template in which the complimentary strand is synthesised. This process ultimately results in what is called gene conversion<ref>Hartl D. L., Ruvolo M. (2012) Genetics, Analysis of Genes and Genomes, Eighth Edition, Burlington, Jones &amp;amp; Bartlett Learning</ref>.  


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Revision as of 00:28, 5 December 2016

 Mismatch repair is the process that occurs in order to repair DNA. Where there are mismatched bases within the DNA molecule, an enzyme will reorganise them.

This is done by cutting out the segment of incorrect base pairs of just one strand of the DNA molecule. The remaining strand then acts as a template in which the complimentary strand is synthesised. This process ultimately results in what is called gene conversion[1].


References

  1. Hartl D. L., Ruvolo M. (2012) Genetics, Analysis of Genes and Genomes, Eighth Edition, Burlington, Jones &amp; Bartlett Learning