GRB2: Difference between revisions
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Growth factor receptor-bound protein 2. | Growth factor receptor-bound protein 2. Found in humans, it is an adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. | ||
Isoform 2 acts as dominant negative protein over GRB2 and by supressinf proliferative signals, may tirgger active programmed cell death. It does so inhibiting EGF-induced transactivation of a RAS-responsive element.<ref>This is a reference to a website about GRB2. http://www.uniprot.org/uniprot/P62993</ref> | |||
=== References === | |||
<references /> | |||
Revision as of 22:11, 2 December 2017
Growth factor receptor-bound protein 2. Found in humans, it is an adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway.
Isoform 2 acts as dominant negative protein over GRB2 and by supressinf proliferative signals, may tirgger active programmed cell death. It does so inhibiting EGF-induced transactivation of a RAS-responsive element.[1]
References
- ↑ This is a reference to a website about GRB2. http://www.uniprot.org/uniprot/P62993