Lethal mutation: Difference between revisions
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This is a mutation that results in the demise of the organism affected<ref>Hartl, D. and Ruvolo, M. (2012). Genetics. Burlington, Mass: Jones and; Bartlett, p.760.</ref>. An example of such a [[mutation|mutation]] can be observed in [[Manx cats|Manx cats]]. Characterised by their lack of tails and longer hind legs, Manx cats carry a [[dominant allele|dominant allele]] (M<sup>L</sup>) that severely affects spinal development. All Manx cats are [[heterozygotes|heterozygotes]]; cats that are [[homozygote|homozygote]] for the M<sup>L</sup> allele do not survive because the [[allele|allele]] is recessive lethal. | |||
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Revision as of 21:39, 4 December 2017
This is a mutation that results in the demise of the organism affected[1]. An example of such a mutation can be observed in Manx cats. Characterised by their lack of tails and longer hind legs, Manx cats carry a dominant allele (ML) that severely affects spinal development. All Manx cats are heterozygotes; cats that are homozygote for the ML allele do not survive because the allele is recessive lethal.
References:
- ↑ Hartl, D. and Ruvolo, M. (2012). Genetics. Burlington, Mass: Jones and; Bartlett, p.760.