Oseltamivir: Difference between revisions
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Oseltamivir is an [[Influenza|influenza]] [[Antiviral medication|antiviral medication]] which is taken orally. It is often sold under the brand name "Tamiflu"<ref>Omudhome Ogbru P. oseltamivir, Tamiflu: Drug Facts, Side Effects, and Dosing. MedicineNet. [cited 3 December 2017]. Available from: https://www.medicinenet.com/oseltamivir/article.htm</ref>. | Oseltamivir is an [[Influenza|influenza]] [[Antiviral medication|antiviral medication]] which is taken orally. It is often sold under the brand name "Tamiflu"<ref>Omudhome Ogbru P. oseltamivir, Tamiflu: Drug Facts, Side Effects, and Dosing. MedicineNet. [cited 3 December 2017]. Available from: https://www.medicinenet.com/oseltamivir/article.htm</ref>. | ||
It is a [[Neuraminidase|neuraminidase]] inhibitor<ref | It is a [[Neuraminidase|neuraminidase]] inhibitor<ref>PubChem. Oseltamivir. 2017 [cited 5/12/17]; | ||
Available from: https://pubchem.ncbi.nlm.nih.gov/compound/oseltamivir#section=Top</ref>. It blocks the [[ | Available from: https://pubchem.ncbi.nlm.nih.gov/compound/oseltamivir#section=Top</ref>. It blocks the [[Active site|active sites]] of neuraminidases, which are [[Enzyme|enzymes]] on the surface of influenza [[Viruses|viruses]] that cleave sialic acid, and prevents the viruses from entering the host cells. It also prevents the release of newly assembled influenza viruses from the host cells. | ||
=== '''Structure of oseltamivir''' === | === '''Structure of oseltamivir''' === | ||
=== [[Image: | === [[Image:Structure of oseltamivir.png]] === | ||
Fig. 1: Structure of oseltamivir<ref | Fig. 1: Structure of oseltamivir<ref>ChemIDplus. Oseltamivir. 2017 [cited 5/12/17]; | ||
Available from: https://chem.nlm.nih.gov/chemidplus/name/oseltamivir</ref> | Available from: https://chem.nlm.nih.gov/chemidplus/name/oseltamivir</ref> | ||
Oseltamivir is an acetamido cyclohexene and its structure is homologous to sialic acid. | Oseltamivir is an acetamido cyclohexene and its structure is homologous to sialic acid. | ||
Influenza viruses use sialic acid as receptors for entering the host cells. | Influenza viruses use sialic acid as receptors for entering the host cells. | ||
=== References === | === References === | ||
<references /><references /><references /> | <references /><references /><references /> | ||
Latest revision as of 00:21, 5 December 2017
Oseltamivir is an influenza antiviral medication which is taken orally. It is often sold under the brand name "Tamiflu"[1].
It is a neuraminidase inhibitor[2]. It blocks the active sites of neuraminidases, which are enzymes on the surface of influenza viruses that cleave sialic acid, and prevents the viruses from entering the host cells. It also prevents the release of newly assembled influenza viruses from the host cells.
Structure of oseltamivir
Fig. 1: Structure of oseltamivir[3]
Oseltamivir is an acetamido cyclohexene and its structure is homologous to sialic acid.
Influenza viruses use sialic acid as receptors for entering the host cells.
References
- ↑ Omudhome Ogbru P. oseltamivir, Tamiflu: Drug Facts, Side Effects, and Dosing. MedicineNet. [cited 3 December 2017]. Available from: https://www.medicinenet.com/oseltamivir/article.htm
- ↑ PubChem. Oseltamivir. 2017 [cited 5/12/17]; Available from: https://pubchem.ncbi.nlm.nih.gov/compound/oseltamivir#section=Top
- ↑ ChemIDplus. Oseltamivir. 2017 [cited 5/12/17]; Available from: https://chem.nlm.nih.gov/chemidplus/name/oseltamivir