Denature: Difference between revisions
Jump to navigation
Jump to search
m fixed some links |
Cleaned up the references. |
||
| Line 1: | Line 1: | ||
When a [[Protein|protein]] is changed in shape and "unfolded", it is said to be denatured. | When a [[Protein|protein]] is changed in shape and "unfolded", it is said to be denatured. This can occur in a number of ways, from a change in environmental factors (i.e. high/low temperature) to the addition of different chemicals (i.e. [[Solvent|solvents]]), causing breaking and changing of integral [[Bond|bonds]] within the protein. | ||
Denaturing is particularly important to consider when studying [[Enzyme|enzymes]]- If a protein's [[Enzyme active site|active site]] is changed so that it is no longer [[Complementary|complementary]] to its [[Substrate|substrate]] then it cannot carry out its function correctly <ref>Alberts, B. Johnson, A. Lewis, J. Raff, M. Roberts, K. Walter, P (2008). Molecular biology of the cell. 5th ed. New York: Garland Science. 130.</ref>. | Denaturing is particularly important to consider when studying [[Enzyme|enzymes]]- If a protein's [[Enzyme active site|active site]] is changed so that it is no longer [[Complementary|complementary]] to its [[Substrate|substrate]] then it cannot carry out its function correctly<ref>Alberts, B. Johnson, A. Lewis, J. Raff, M. Roberts, K. Walter, P (2008). Molecular biology of the cell. 5th ed. New York: Garland Science. 130.</ref>. | ||
=== References === | === References === | ||
<references / | <references /> | ||
Latest revision as of 08:26, 5 December 2017
When a protein is changed in shape and "unfolded", it is said to be denatured. This can occur in a number of ways, from a change in environmental factors (i.e. high/low temperature) to the addition of different chemicals (i.e. solvents), causing breaking and changing of integral bonds within the protein.
Denaturing is particularly important to consider when studying enzymes- If a protein's active site is changed so that it is no longer complementary to its substrate then it cannot carry out its function correctly[1].
References
- ↑ Alberts, B. Johnson, A. Lewis, J. Raff, M. Roberts, K. Walter, P (2008). Molecular biology of the cell. 5th ed. New York: Garland Science. 130.