Presynaptic neurone: Difference between revisions
Cleaned up the text. Reformatted the page. Cleaned up the references. |
No edit summary |
||
| Line 1: | Line 1: | ||
The presynaptic neurone is the | The presynaptic neurone is a neuron from the axon terminal of which an electrical impulse is transmitted across a synaptic cleft to the cell body or one or more dendrites of a postsynaptic neuron by the release of a chemical neurotransmitter; an example is acetylcholine [1]. | ||
When an [[Action potential|action potential arrives]] at the [[Axon terminal|axon terminal]] of the presynaptic membrane, [[ | When an [[Action potential|action potential arrives]] at the [[Axon terminal|axon terminal]] of the presynaptic membrane, [[Calcium ion channel|Ca<sup>2+</sup> ion channels]] open, allowing the ions to move into the cell down their [[Concentration Gradient|concentration gradient]]. This, in turn, causes the neurotransmitter containing [[Vesicles|vesicles]] to translocate and fuse to the [[Presynaptic membrane|presynaptic membrane]]. The neurotransmitter diffuses across the synapse and starts a new action potential in the postsynaptic neurone<ref>Purves D, Augustine GJ, Fitzpatrick D, et al., editors. Neuroscience. 2nd edition. Sunderland (MA): Sinauer Associates; 2001. Excitatory and Inhibitory Postsynaptic Potentials. Available from: https://www.ncbi.nlm.nih.gov/books/NBK11117/accessed 17/11/17</ref>. | ||
=== Reference === | === Reference === | ||
[1] Anon, (2017). [online] Available at: https://medical-dictionary.thefreedictionary.com/presynaptic+neuron|Anon, (2017). [online] Available at: https://medical-dictionary.thefreedictionary.com/presynaptic+neuron]<br> | |||
Revision as of 22:20, 5 December 2017
The presynaptic neurone is a neuron from the axon terminal of which an electrical impulse is transmitted across a synaptic cleft to the cell body or one or more dendrites of a postsynaptic neuron by the release of a chemical neurotransmitter; an example is acetylcholine [1].
When an action potential arrives at the axon terminal of the presynaptic membrane, Ca2+ ion channels open, allowing the ions to move into the cell down their concentration gradient. This, in turn, causes the neurotransmitter containing vesicles to translocate and fuse to the presynaptic membrane. The neurotransmitter diffuses across the synapse and starts a new action potential in the postsynaptic neurone[1].
Reference
[1] Anon, (2017). [online] Available at: https://medical-dictionary.thefreedictionary.com/presynaptic+neuron%7CAnon, (2017). [online] Available at: https://medical-dictionary.thefreedictionary.com/presynaptic+neuron]
- ↑ Purves D, Augustine GJ, Fitzpatrick D, et al., editors. Neuroscience. 2nd edition. Sunderland (MA): Sinauer Associates; 2001. Excitatory and Inhibitory Postsynaptic Potentials. Available from: https://www.ncbi.nlm.nih.gov/books/NBK11117/accessed 17/11/17